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[己酮可可碱对慢性呼吸衰竭血液流变学及凝血变化的影响]

[Pentoxifylline in the blood rheological and coagulative changes in chronic respiratory failure].

作者信息

Micillo E, Dericoloso A, Tranchese D, Bianco A, Sorrentino L, Di Filippo O

机构信息

I Facoltà di Medicina e Chirurgia, Istituto di Clinica Tisiologica e dell'Apparato Respiratorio, Università degli Studi di Napoli.

出版信息

Arch Monaldi Mal Torace. 1990 Jan-Feb;45(1):31-8.

PMID:1669259
Abstract

In this study, some hemorheological and coagulative parameters (blood viscosity, erythrocyte filtrability, CPA, platelet aggregation) have been evaluated in 40 patients with Chronic Respiratory Failure. The results obtained document in these patients, important hemorheologic changes. 11 patients with most serious rheologic changes have been treated with Pentossifillina. A significative improvement of the explored parameters and of the clinical condition has been checked after treatment.

摘要

在本研究中,对40例慢性呼吸衰竭患者的一些血液流变学和凝血参数(血液粘度、红细胞滤过率、纤溶酶原激活物、血小板聚集)进行了评估。所得结果证明这些患者存在重要的血液流变学变化。11例血液流变学变化最严重的患者接受了己酮可可碱治疗。治疗后检查发现所探究的参数及临床状况有显著改善。

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