Eberle E, Doering A, Keil U
GSF-Forschungszentrum für Umwelt und Gesundheit (GSF), Institute of Epidemiology, Neuherberg, Federal Republic of Germany.
Ann Epidemiol. 1991 Nov;1(6):487-92. doi: 10.1016/1047-2797(91)90020-d.
Data from the MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Augsburg cohort were used to study the effect of weight change on changes in serum levels of total and high-density-lipoprotein cholesterol. Weight gain was associated with rising levels of total cholesterol and falling levels of high-density-lipoprotein cholesterol in both sexes, more so in men than in women. Moreover, these relationships weakened with advancing age in women, but not in men. The results support the view that weight loss may more favorably affect lipid levels in men than in women, particularly at older ages.
来自奥格斯堡心血管疾病监测趋势和决定因素(MONICA)队列的数据被用于研究体重变化对血清总胆固醇和高密度脂蛋白胆固醇水平变化的影响。体重增加与男女两性的总胆固醇水平升高和高密度脂蛋白胆固醇水平降低相关,男性的相关性比女性更强。此外,这些关系在女性中随年龄增长而减弱,但在男性中并非如此。结果支持这样一种观点,即体重减轻对男性血脂水平的影响可能比对女性更有利,尤其是在老年时。