Fathelrahman A I, Ab Rahman A F, Zain Z Mohd, Tengku M A
Drug Information Centre, Directorate of Pharmacy, Ministry of Health Khartoum State, PO. Box 1517, Khartoum, Sudan.
Hum Exp Toxicol. 2006 Apr;25(4):167-73. doi: 10.1191/0960327106ht606oa.
Data on adult risk factors associated with drug or chemical poisonings in Malaysia are scarce. The objective of the study was to identify possible risk factors associated with adult admissions to the Penang General Hospital (PGH) due to chemical poisoning and/or drug overdose. The present study was a case-control study, conducted over 18 weeks. One hundred acutely poisoned adult patients admitted to PGH during the period from September 2003 to February 2004 were considered as cases. Two hundred patients admitted to the same medical wards for other illnesses, during the same period, were matched for age and gender with the poisoned cases and thus selected as controls. McNemar test and binary logistic were used for univariate analysis and logistic regression analysis for multivariate analyses. The odds ratio (OR) and its 95% confidence interval (95% CI) were calculated for each predictor variable. Positive histories of psychiatric illness and previous poisoning, problems in boy/girl friend relationships, family problems, marital problems, Indian ethnicity, Chinese ethnicity, living in rented houses and living in a household with less than five people were significant risk factors associated with adult admissions due to poisoning.
马来西亚关于与药物或化学中毒相关的成人风险因素的数据很少。本研究的目的是确定槟城总医院（PGH）成人因化学中毒和/或药物过量入院的可能风险因素。本研究是一项病例对照研究，为期18周。2003年9月至2004年2月期间入住PGH的100名急性中毒成年患者被视为病例。同期因其他疾病入住同一病房的200名患者，按年龄和性别与中毒病例匹配，因此被选为对照。采用McNemar检验和二元逻辑回归进行单因素分析，采用逻辑回归分析进行多因素分析。计算每个预测变量的比值比（OR）及其95%置信区间（95%CI）。精神疾病史和既往中毒史、男女朋友关系问题、家庭问题、婚姻问题、印度族裔、华裔、居住在出租屋以及居住在人口少于五人的家庭中是与成人中毒入院相关的显著风险因素。
