McMoli T E, Assonganyi T
C.U.S.S. Yaounde, Cameroon.
Rev Int Trach Pathol Ocul Trop Subtrop Sante Publique. 1991;68:157-70.
Limbal Vernal kerato-conjunctivitis is the 6th most frequent diagnosis in the Ophthalmology service of CHU, Yaounde, Cameroon, and accounts for 2.8% of all clinic consultations. Only grades I and II of the disease (Diallo's classification) are found in this forest zone of Africa. Advanced stages which may cause corneal blindness being probably due to absence of xerophthalmia in this part of Africa. Both sexes are equally affected. Association with other allergic diseases is very rare and there is no hereditary tendency. Serum and tear Immunoglobulin assays in patients and controls of the same parent-hood showed no statistical differences (P > 0.05). Mast cell immunocytological studies might be more rewarding. Relief of pruritus is best with sodium cromoglycate and Naaga. However, in severe cases interrupted systemic steroids (not exceeding one week each time) are utilized. Poor drug compliance, due to costs is frequent; probably cautious cryo application in severe cases, might together with infrequent Naaga or sodium cromoglycate, procure longer remissions.
角膜缘春季角结膜炎是喀麦隆雅温得CHU眼科门诊第六常见的诊断疾病，占所有门诊咨询的2.8%。在非洲的这片森林地区仅发现该病的I级和II级（迪亚洛分类法）。可能导致角膜盲的晚期阶段在非洲这一地区可能是由于不存在干眼病。男女受影响程度相同。与其他过敏性疾病的关联非常罕见，且无遗传倾向。对来自同一家庭的患者和对照进行血清和泪液免疫球蛋白检测，结果无统计学差异（P>0.05）。肥大细胞免疫细胞学研究可能更有意义。色甘酸钠和那加对缓解瘙痒效果最佳。然而，在严重病例中，会使用间断性全身类固醇（每次不超过一周）。由于费用问题，药物依从性差很常见；在严重病例中，谨慎应用冷冻疗法，可能与较少使用那加或色甘酸钠一起，能获得更长时间的缓解。
