Newton L, Hall S M, Pelerin M, McLauchlin J
CDR (Lond Engl Rev). 1991 Sep 13;1(10):R110-3.
The annual numbers of reports of listeriosis in England, Wales and Northern Ireland received by the PHLS Communicable Disease Surveillance Centre (CDSC) and the Division of Microbiological Reagents (DMR) have shown remarkable changes in recent years. There was a near doubling in 1987 compared to 1986; a further increase in 1988; a sharp decline in 1989 (which occurred in the second half of that year) and, finally, the total in 1990 was the lowest since 1984. The rise and fall particularly (but not exclusively) involved pregnancy-associated cases and illness caused by serotype 4. The epidemiological and clinical features reported in 1990 were otherwise similar to those reported in previous years and in other countries. Patients with the non pregnancy-associated (also called 'adult/juvenile') type were in the majority, most of whom had an underlying disorder associated with impaired immunity. The reason for the changes in reported incidence is not completely understood but is probably due to the emergence and disappearance of a common food source of the organism. There is, however, no cause for complacency. Diagnostic vigilance must be maintained and vulnerable groups should adhere to existing dietary advice.
英国公共卫生实验室服务中心传染病监测中心（CDSC）和微生物试剂部（DMR）收到的关于英格兰、威尔士和北爱尔兰李斯特菌病的年度报告数量近年来呈现出显著变化。与1986年相比，1987年报告数量几乎翻了一番；1988年进一步增加；1989年急剧下降（发生在该年下半年），最后，1990年的总数是1984年以来最低的。这种上升和下降尤其（但不限于）涉及与妊娠相关的病例以及由4型血清型引起的疾病。1990年报告的流行病学和临床特征与前几年以及其他国家报告的情况相似。非妊娠相关（也称为“成人/青少年”）类型的患者占大多数，其中大多数人有一种与免疫功能受损相关的潜在疾病。报告发病率变化的原因尚未完全明了，但可能是由于该病原体常见食物来源的出现和消失。然而，仍不能掉以轻心。必须保持诊断警惕性，弱势群体应遵循现有的饮食建议。
