发育过程中的基因表达分析：来自顶复门的经验教训。
Analysis of gene expression during development: lessons from the Apicomplexa.
作者信息
Boyle Jon P, Saeij Jeroen P J, Cleary Michael D, Boothroyd John C
机构信息
Department of Microbiology and Immunology, Fairchild Building D305, Stanford University School of Medicine, 299 Campus Drive, Stanford, CA 94305-5124, USA.
出版信息
Microbes Infect. 2006 May;8(6):1623-30. doi: 10.1016/j.micinf.2005.11.017. Epub 2006 Jan 25.
Apicomplexans are responsible for significant human and animal disease worldwide, including malaria and toxoplasmosis. Herein we summarize recent advances in gene expression analysis in these eukaryotic pathogens, especially with respect to their developmental biology, and discuss the impact this work may have on the development of new vaccines and chemotherapeutics.
顶复门原虫在全球范围内引发了严重的人类和动物疾病，包括疟疾和弓形虫病。在此，我们总结了这些真核病原体基因表达分析的最新进展，特别是关于它们的发育生物学方面的进展，并讨论这项工作可能对新型疫苗和化疗药物研发产生的影响。
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