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用于矫正近视散光的Q值定制消融轮廓。

Q-factor customized ablation profile for the correction of myopic astigmatism.

作者信息

Koller Tobias, Iseli Hans Peter, Hafezi Farhad, Mrochen Michael, Seiler Theo

机构信息

Institut für Refraktive und Ophthalmo-Chirurgie, Zürich, Switzerland.

出版信息

J Cataract Refract Surg. 2006 Apr;32(4):584-9. doi: 10.1016/j.jcrs.2006.01.049.

Abstract

PURPOSE

To compare the results of the Q-factor customized aspheric ablation profile with the wavefront-guided customized ablation pattern for the correction of myopic astigmatism.

SETTING

Institute for Refractive and Ophthalmic Surgery, Zurich, Switzerland.

METHODS

Thirty-five patients were enrolled in a controlled study in which the nondominant eye was treated with the Q-factor customized profile (custom-Q study group) and the dominant eye was treated with wavefront-guided customized ablation (control group). Preoperative and 1-month postoperative high-contrast visual acuity, low-contrast visual acuity, and glare visual acuity, as well as aberrometry and asphericity of the cornea, were compared between the 2 groups. All eyes received laser in situ keratomileusis surgery, and the laser treatment was accomplished with the Wavelight Eye-Q 400 Hz excimer laser.

RESULTS

For corrections up to -9 diopters (D) of myopia, there were no statistically significant differences between the 2 groups regarding any visual or optical parameter except coma-like aberrations (3rd Zernike order), where the wavefront-guided group was significantly better 1 month after surgery (P = .002). For corrections up to -5 D (spherical equivalent), the Q-factor optimized treated eyes had a significantly smaller shift toward oblate cornea: DeltaQ15 = 0.25 in Q-factor customized versus DeltaQ15 = 0.38 in wavefront-guided treatment (P = .04).

CONCLUSIONS

Regarding safety and refractive efficacy, custom-Q ablation profiles were clinically equivalent to wavefront-guided profiles in corrections of myopia up to -9 D and astigmatism up to 2.5 D. Corneal asphericity was less impaired by the custom-Q treatment up to -5 D of myopia.

摘要

目的

比较用于矫正近视散光的Q值定制非球面消融曲线与波前引导定制消融模式的结果。

设置

瑞士苏黎世屈光与眼科手术研究所。

方法

35例患者参与一项对照研究,其中非优势眼采用Q值定制曲线治疗(定制-Q研究组),优势眼采用波前引导定制消融治疗(对照组)。比较两组术前及术后1个月的高对比度视力、低对比度视力和眩光视力,以及角膜像差和非球面性。所有眼睛均接受准分子原位角膜磨镶术,激光治疗采用威视400Hz准分子激光完成。

结果

对于近视矫正度数达-9屈光度(D),两组在任何视觉或光学参数上均无统计学显著差异,但在彗差样像差(第3阶泽尼克系数)方面除外,术后1个月波前引导组明显更好(P = 0.002)。对于等效球镜度达-5D的矫正,Q值优化治疗的眼睛向扁平角膜的偏移明显更小:定制-Q组的DeltaQ15 = 0.25,而波前引导治疗组的DeltaQ15 = 0.38(P = 0.04)。

结论

在安全性和屈光效果方面,定制-Q消融曲线在矫正近视达-9D和散光达2.5D时在临床上与波前引导曲线等效。在近视矫正度数达-5D时,定制-Q治疗对角膜非球面性的损害较小。

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