Zhang Jun, Zheng Li, Zhao Xia, Xu Yang, Chen Shu
HangZhou Bright Vision Hospital, ZheJiang Province, China.
J Curr Ophthalmol. 2016 Sep 3;28(4):181-187. doi: 10.1016/j.joco.2016.08.004. eCollection 2016 Dec.
The aim of this study was to compare the changes in corneal biomechanical properties following small-incision lenticule extraction (SMILE) versus Q-value-guided femtosecond laser-assisted keratomileusis (Q-FS-LASIK).
In this prospective comparative study, patients with a sphere plus cylinder measurement of less than -10.00 D and cylinder measurement of less than -5.00 D were included in the study. A total of 160 patients (160 eyes) with myopia and myopic astigmatism were divided into the two groups, with 80 patients (80 eyes) allocated to SMILE and 80 patients (80 eyes) allocated to Q-FS-LASIK. Corneal hysteresis (CH) and the corneal resistance factor (CRF) were quantitatively assessed using the Ocular Response Analyzer (ORA) preoperatively and at 1 day, 2 weeks, and 1 and 3 months postoperatively.
Both types of surgery were associated with statistically significant decreases in CH and the CRF at postoperative day 1 (both P < 0.01). In both groups, the decreases subsequently stabilized with no further deteriorations compared to postoperative day 1 (P > 0.05). Both groups showed similar biomechanical changes at each time point (all P > 0.05).
Both SMILE and Q-FS-LASIK resulted in a decrease in CH and the CRF at postoperative 1 day, with the decreases stabilizing after this point. There were no significant differences between the short term effects of SMILE and Q-FS-LASIK on corneal biomechanical properties.
本研究旨在比较小切口透镜切除术(SMILE)与Q值引导的飞秒激光原位角膜磨镶术(Q-FS-LASIK)后角膜生物力学特性的变化。
在这项前瞻性比较研究中,纳入球镜加柱镜测量值小于-10.00 D且柱镜测量值小于-5.00 D的患者。总共160例近视和近视散光患者(160只眼)被分为两组,80例患者(80只眼)分配至SMILE组,80例患者(80只眼)分配至Q-FS-LASIK组。术前以及术后1天、2周、1个月和3个月使用眼反应分析仪(ORA)定量评估角膜滞后(CH)和角膜阻力因子(CRF)。
两种手术方式在术后第1天均与CH和CRF的统计学显著降低相关(均P < 0.01)。在两组中,与术后第1天相比,这些降低随后稳定下来,没有进一步恶化(P > 0.05)。两组在每个时间点均显示出相似的生物力学变化(均P > 0.05)。
SMILE和Q-FS-LASIK均导致术后1天CH和CRF降低,此后降低趋于稳定。SMILE和Q-FS-LASIK对角膜生物力学特性的短期影响之间无显著差异。