Patel Seema R, Hammersmith Kristin M, Rapuano Christopher J, Cohen Elisabeth J
Cornea Service, Wills Eye Hospital, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
J Cataract Refract Surg. 2006 Apr;32(4):681-4. doi: 10.1016/j.jcrs.2006.01.040.
A 52-year-old man had laser in situ keratomileusis in March 2002 and 2 weeks later had a corneal infection that was found to be caused by Exophiala dermatitidis. This infection waxed and waned for 9 months despite therapy with natamycin, itraconazole, and fluconazole but eventually responded to topical amphotericin. He recovered good visual acuity in this eye with a rigid gas-permeable lens. This case shows the importance of selecting the appropriate agent in fungal keratitis.
一名52岁男性于2002年3月接受了准分子原位角膜磨镶术,两周后发生角膜感染,经检查发现由皮炎外瓶霉引起。尽管使用了那他霉素、伊曲康唑和氟康唑进行治疗,这种感染仍持续了9个月,病情反复,但最终对局部使用两性霉素有反应。他通过佩戴硬性透气性角膜接触镜,这只眼睛恢复了良好的视力。该病例显示了在真菌性角膜炎中选择合适药物的重要性。