Zhang Xu-Sheng, Hill William G
Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, West Mains Road, Edinburgh, UK, EH9 3JT.
Trends Ecol Evol. 2005 Sep;20(9):468-70. doi: 10.1016/j.tree.2005.06.010. Epub 2005 Jul 6.
A fundamental problem in evolutionary genetics is understanding how high levels of genetic variation in quantitative traits are maintained in natural populations. Variation is removed by the natural selection of individuals with optimal phenotypes and is recovered by mutation; however, previous analyses had indicated that a mutation-selection balance was insufficient to maintain observed levels of genetic variation in these traits. Using more general models, however, it has recently been shown that it is indeed a sufficient mechanism. These models can be used to explore other phenomena in evolutionary biology.
进化遗传学中的一个基本问题是理解自然种群中数量性状的高遗传变异水平是如何维持的。具有最优表型的个体通过自然选择被淘汰，变异则通过突变得以恢复；然而，先前的分析表明，突变 - 选择平衡不足以维持这些性状中所观察到的遗传变异水平。然而，使用更通用的模型最近已表明，这确实是一种充分的机制。这些模型可用于探索进化生物学中的其他现象。
