Brétagnol Frédéric, Lejeune Michaël, Papadopoulou-Bouraoui Andri, Hasiwa Marina, Rauscher Hubert, Ceccone Giacomo, Colpo Pascal, Rossi François
Institute for Health and Consumer Protection (IHCP), Joint Research Centre, European Commission, IHCP, TP 203, I-21020 Ispra (VA), Italy.
Acta Biomater. 2006 Mar;2(2):165-72. doi: 10.1016/j.actbio.2005.11.002. Epub 2006 Jan 4.
This paper presents the results of plasma polymerization using diethylene glycol dimethyl ether as a precursor in a capacitively coupled radio frequency system. The chemical structure of the coatings was characterized using several analysis techniques (X-ray photoelectron spectroscopy, Fourier transform-infrared spectroscopy, ellipsometry), while the biological response of these coatings has been tested by protein adsorption and cell culture experiments. The modulation of the input plasma power controls the concentration of polyethylene oxide groups in the coatings and allows the production of films with opposite protein and cell repellent properties. The study of the stability of these coatings in different media (water, acetone, phosphate-buffered saline) reveals that these films could be involved in classical lift-off processes for the production of patterned surfaces.
本文介绍了在电容耦合射频系统中使用二甘醇二甲醚作为前驱体进行等离子体聚合的结果。采用多种分析技术（X射线光电子能谱、傅里叶变换红外光谱、椭偏仪）对涂层的化学结构进行了表征，同时通过蛋白质吸附和细胞培养实验测试了这些涂层的生物学响应。输入等离子体功率的调节控制了涂层中聚环氧乙烷基团的浓度，并使得能够制备出具有相反蛋白质和细胞排斥特性的薄膜。对这些涂层在不同介质（水、丙酮、磷酸盐缓冲盐水）中的稳定性研究表明，这些薄膜可用于图案化表面生产的经典剥离工艺。
