Kirchmann Malene
Danish Headache Center, Department of Neurology, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark.
Curr Opin Neurol. 2006 Jun;19(3):286-93. doi: 10.1097/01.wco.0000227040.16071.a9.
To discuss the consequences of recent clinical data on migraine with aura for clinical practice and future research in the light of new diagnostic criteria for migraine with aura.
Migraine with aura is now distinguished from hemiplegic migraine and from basilar migraine. Migraine with typical aura has an aura consisting of visual, sensory, or speech symptoms. The aura symptoms typically develop gradually over 5 or more minutes, last between 5 and 60 minutes and, when more than one symptom is present, they occur in succession. Half-sidedness is typical of visual and sensory symptoms, whereas speech symptoms are typically aphasic, primarily of the Broca type. A visual aura rating scale with a high sensitivity and specificity has been developed to standardize the diagnosis of visual aura. The new classification, the new criteria, and the new knowledge about clinical features of migraine with aura are important both for routine clinical diagnosis and for future research studies.
Recent studies of the clinical features of migraine with aura allow a more precise diagnosis and classification than previously possible. A clear distinction between migraine with typical aura, hemiplegic migraine, and basilar migraine is important for genetic and other research studies.
根据先兆性偏头痛的新诊断标准，探讨近期临床数据对先兆性偏头痛临床实践和未来研究的影响。
先兆性偏头痛现已与偏瘫性偏头痛和基底型偏头痛区分开来。典型先兆性偏头痛的先兆包括视觉、感觉或言语症状。先兆症状通常在5分钟或更长时间内逐渐出现，持续5至60分钟，当存在多种症状时，它们会相继出现。视觉和感觉症状通常为单侧性，而言语症状通常为失语，主要是布罗卡失语类型。已开发出一种具有高灵敏度和特异性的视觉先兆评定量表，以规范视觉先兆的诊断。先兆性偏头痛的新分类、新标准以及关于其临床特征的新知识，对于常规临床诊断和未来研究都很重要。
近期对先兆性偏头痛临床特征的研究使得诊断和分类比以往更加精确。明确区分典型先兆性偏头痛、偏瘫性偏头痛和基底型偏头痛对于遗传学及其他研究很重要。
