Petrusic Igor, Pavlovski Vera, Vucinic Dragana, Jancic Jasna
Faculty of Medicine, University of Belgrade, Doktora Subotica 8, 11000 Belgrade, Serbia.
J Headache Pain. 2014 Dec 12;15(1):87. doi: 10.1186/1129-2377-15-87.
Complex migraine aura in teenagers can be complicated to diagnose. The aim of this study was to present detailed features of migraine aura in teenage migraineurs.
This cross-sectional study was conducted in the period from 2008 till 2013. A total number of 40 teenage migraineurs (20 females and 20 males) met criteria for this study. The patients were interviewed using a specially designed questionnaire for collecting data about migraine aura features. Main outcome measures were frequency of visual, somatosensory and higher cortical dysfunction (HCD) symptoms in teenage migraineurs population during the aura, and also within each individual.
Visual aura was reported in every attack, followed by somatosensory (60%) and dysphasic (36.4%) aura. Scintillating scotoma and blurry vision were mostly reported and predominant visual symptoms. The most common somatosensory symptom was numbness in hand. HCD were reported by 22 (55%) patients. Slowed speech was mostly reported symptom of HCD, followed by dyslexia, déjà vu phenomenon, color dysgnosia, and dyspraxia. In patients with HCD, aura frequency per year (6.18 ± 3.17 vs. 3.33 ± 2.03, p = 0.003) and prevalence of somatosensory symptoms (77.3% vs. 38.9%, p = 0.014) were significantly higher than in patients without HCD.
Aura symptoms vary to a great extent in complexity in teenage migraineurs. Consequently, results obtained in this study provide useful information for clinicians when faced with unusual migraine aura.
青少年复杂性偏头痛先兆的诊断可能较为复杂。本研究的目的是呈现青少年偏头痛患者偏头痛先兆的详细特征。
这项横断面研究于2008年至2013年期间进行。共有40名青少年偏头痛患者（20名女性和20名男性）符合本研究标准。使用专门设计的问卷对患者进行访谈，以收集有关偏头痛先兆特征的数据。主要观察指标为青少年偏头痛患者群体在先兆期间以及每个个体中视觉、躯体感觉和高级皮质功能障碍（HCD）症状的发生频率。
每次发作均报告有视觉先兆，其次是躯体感觉先兆（60%）和言语困难先兆（36.4%）。闪烁暗点和视力模糊是最常报告的主要视觉症状。最常见的躯体感觉症状是手部麻木。22名（55%）患者报告有HCD。言语迟缓是HCD最常报告的症状，其次是诵读困难、似曾相识现象、颜色失认症和失用症。有HCD的患者每年的先兆发作频率（6.18±3.17对3.33±2.03，p=0.003）和躯体感觉症状的患病率（77.3%对38.9%，p=0.014）显著高于无HCD的患者。
青少年偏头痛患者的先兆症状在复杂性上有很大差异。因此，本研究结果为临床医生面对不寻常的偏头痛先兆时提供了有用信息。
