Scharmach M, Neumann V, Müller K-M, Fischer M
Deutsches Mesotheliomregister, Bochum.
Pneumologie. 2006 May;60(5):277-83. doi: 10.1055/s-2006-932132.
Starting with the question whether there is a principal difference in the metastatic behaviour of pleural mesothelioma and pulmonary tumors, a detailed retrospective study of the findings of 210 post-mortem examinations between the years of 1992 to 1999 was conducted. The spectrum of metastatic sites is very large in malignant pulmonary carcinomas (n = 148) as well as in malignant pleural mesotheliomas (n = 62). There is no significant difference in the TMN-staging between both tumor groups at the time of death. One exception was the brain: there were significantly more metastases from the pulmonary tumors. Carcinomas metastasized more frequently into the skeleton, the kidneys and the adrenal glands, while metastases of mesotheliomas were more often found in the peritoneum. As of the moment there is no significant difference in the pattern of metastasis between both tumor groups discernible.
从胸膜间皮瘤和肺部肿瘤的转移行为是否存在主要差异这一问题出发,对1992年至1999年间210例尸检结果进行了详细的回顾性研究。恶性肺癌(n = 148)和恶性胸膜间皮瘤(n = 62)的转移部位范围都非常广泛。两组肿瘤在死亡时的TMN分期没有显著差异。一个例外是脑:肺部肿瘤转移至脑的情况明显更多。癌转移至骨骼、肾脏和肾上腺更为频繁,而间皮瘤的转移则更常见于腹膜。目前,两组肿瘤之间的转移模式没有明显差异。