[阴茎扁平苔藓引发的疣状癌。一种真正的癌前病变？]
[Verrucous carcinoma of the penis arising from a lichen planus. A true preneoplastic lesion?].
作者信息
Alvarez Alvarez C, Meijide Rico F, Rodríguez González L, Antón Badiola I, Zungri Telo E, Antonio Ortiz-Rey J
机构信息
Servicio de Anatomia Patológica, Hospital Povisa, Vigo, Pontevedra.
出版信息
Actas Urol Esp. 2006 Jan;30(1):90-2. doi: 10.4321/s0210-48062006000100015.
INTRODUCTION
Up to 30% of squamous cell carcinomas of the penis arise from a lichen sclerosus, but very few reports in which lichen planus was the preexisting lesion have been published. We report a male with verrucous carcinoma of penis that developed in an area of lichen planus.
CLINICAL CASE
A 53-year-old male presented with an exophytic tumor on the glans penis that had been present for about 6 months. The lesion developed in a previously biopsied area of lichen planus hypertrophicus. After excision, histological diagnosis was verrucous carcinoma.
COMMENT
The development of any subtype of squamous cell carcinoma of penis in a lichen planus can be coincidental, or a neoplastic transformation of lichen planus can take place.
引言
高达30%的阴茎鳞状细胞癌起源于硬化性苔藓，但仅有极少关于扁平苔藓作为前驱病变的报道发表。我们报告一例阴茎疣状癌发生于扁平苔藓区域的男性病例。
临床病例
一名53岁男性，阴茎龟头出现外生性肿物约6个月。该病变发生于先前活检的肥厚性扁平苔藓区域。切除术后，组织学诊断为疣状癌。
评论
阴茎鳞状细胞癌的任何亚型在扁平苔藓中发生可能是巧合，也可能是扁平苔藓发生了肿瘤转化。
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