扁平苔藓区域的阴蒂疣状癌具有侵袭性特征。
A clitoral verrucous carcinoma in an area of lichen planus has aggressive features.
作者信息
Tjalma Wiebren A A, Siozopoulou Vasiliki, Huizing Manon T
机构信息
Department of Obstetrics and Gynecology, Multidisciplinary Breast Clinic, Gynecological Oncology Unit, Antwerp University Hospital - University of Antwerp, Wilrijkstraat 10, Edegem, 2650, Belgium.
出版信息
World J Surg Oncol. 2017 Jan 6;15(1):7. doi: 10.1186/s12957-016-1069-0.
BACKGROUND
Verrucous carcinoma of the vulva is extremely rare. It is a slow growing, low malignant variant of a squamous cell carcinoma with a cauliflower appearance. Women with lichen planus have an increased risk of developing vulval cancer.
CASE PRESENTATION
A 79-year-old woman consulted for vulval itching. On clinical examination, a 3-cm large verrucous clitoral cancer in an area of lichen planus was seen. Based on her last clinical examination, the growth was estimated to be 1 cm per month with an invasion depth after 6 months of 5 mm. A tumor developing in an area of lichen planus appears to have more aggressive features. This is the first time that the growth of a verrucous carcinoma has been documented in an area of lichen planus.
CONCLUSIONS
Clinicians and patients should be aware of the aggressive behavior of cancers developing in areas of lichen planus and adjust their surgical management together with the follow-up strategy.
背景
外阴疣状癌极为罕见。它是鳞状细胞癌的一种生长缓慢、低恶性的变体，外观呈菜花状。扁平苔藓女性患外阴癌的风险增加。
病例介绍
一名79岁女性因外阴瘙痒前来就诊。临床检查发现，在扁平苔藓区域有一个3厘米大的疣状阴蒂癌。根据她上次的临床检查，肿瘤生长速度估计为每月1厘米，6个月后浸润深度为5毫米。在扁平苔藓区域发生的肿瘤似乎具有更具侵袭性的特征。这是首次记录到疣状癌在扁平苔藓区域的生长情况。
结论
临床医生和患者应意识到在扁平苔藓区域发生的癌症具有侵袭性，并共同调整手术治疗及随访策略。
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