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[结痂及液体环境下大鼠烧伤创面愈合过程中表皮细胞合成活性的变化]

[Change in synthetic activity of epidermis cells in rats during burn wound healing under a scab and in liquid environment].

作者信息

Kholmogorskaia O V, Ivanishchuk P P, Surakova T V

出版信息

Tsitologiia. 2005;47(5):388-92.

Abstract

One of the problems of burn treatment is a creation of conditions providing most valuable skin rehabilitation. An experimental model of burn wound healing in a 0.9% NaCl solution is proposed. Synthetic activity of rat epidermis cells in the process of burn wound healing under a scab and in liquid environment was studied by luminescent microscopy. The effect of a 0.9% NaCl solution involves an increase of the basal layer cell synthetic activity of regenerating epidermis, and keeping a high level of this activity of hair follicle epithelial cells for a long time. Tissue-preserving effect of the 0.9% NaCl solution on burns healing has been confirmed in these results.

摘要

烧伤治疗的问题之一是创造条件以实现最有价值的皮肤修复。本文提出了在0.9%氯化钠溶液中烧伤创面愈合的实验模型。通过荧光显微镜研究了大鼠表皮细胞在痂下和液体环境中烧伤创面愈合过程中的合成活性。0.9%氯化钠溶液的作用包括提高再生表皮基底层细胞的合成活性,并使毛囊上皮细胞的这种活性长时间保持在较高水平。这些结果证实了0.9%氯化钠溶液对烧伤愈合的组织保护作用。

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