Balkrishnan Rajesh, Kulkarni Amit S, Cayce Kimberly, Feldman Steven R
Department of Pharmacy Practice and Administration, Ohio State University College of Pharmacy, Columbus 43210, USA.
Cutis. 2006 Apr;77(4):251-5.
This study investigated the relationship among health status, costs linked with the treatment of acne in the United States, and other aspects related to medication use. The US Medical Expenditure Panel Survey (MEPS) database was analyzed for a cohort of people with acne. This cross-sectional study obtained costs, demographics, healthcare service utilization, and clinical patient variables from the MEPS database. The EuroQol Group's EQ-5D scores available in MEPS were used for health status information. Multivariate weighted analysis was performed for data for approximately 5 million patients (weighted sample size). Nearly 70% of the patients used some type of medication for acne. Acne-related medication accounted for approximately 36% of the total acne-related annual healthcare costs, with an average of 2 annual acne prescription refills per patient. Increased number of refills of acne-related medications was associated with an improvement in health status (P<.05). Increased physician office-based visits were the only predictors of higher acne-related annual healthcare costs (P<.01). Adherence to acne medications is an important component of better health status. Pharmacologic treatment of acne does not significantly add to acne-related annual healthcare costs.
本研究调查了美国健康状况、痤疮治疗相关费用以及与药物使用相关的其他方面之间的关系。对美国医疗支出面板调查（MEPS）数据库中一组痤疮患者进行了分析。这项横断面研究从MEPS数据库中获取了费用、人口统计学信息、医疗服务利用情况以及临床患者变量。利用MEPS中可获得的欧洲生活质量小组的EQ - 5D评分作为健康状况信息。对约500万患者的数据（加权样本量）进行了多变量加权分析。近70%的患者使用了某种类型的痤疮药物。痤疮相关药物约占痤疮相关年度医疗总费用的36%，每位患者平均每年有2次痤疮处方续配。痤疮相关药物续配次数增加与健康状况改善相关（P<0.05）。增加基于医生办公室的就诊次数是痤疮相关年度医疗费用较高的唯一预测因素（P<0.01）。坚持使用痤疮药物是改善健康状况的一个重要组成部分。痤疮的药物治疗不会显著增加痤疮相关的年度医疗费用。
