Gainor Rachael E, Fitch Cindy, Pollard Cecil
Office of Health Services Research, Dept. of Community Medicine, West Virginia University School of Medicine, Morgantown, USA.
W V Med J. 2006 Jan-Feb;102(1):314-6.
Diabetes Mellitus (DM) is a serious problem in West Virginia. Diabetes during pregnancy has been associated with several negative outcomes. This study tested the hypotheses that women who had DM during pregnancy would have more negative perinatal outcomes than those who did not and women with pre-gestational DM would have more negative perinatal outcomes than women with gestational DM. The population included 14,583 mothers enrolled in WV Medicaid in 2001 and 2002. The population was divided according to the presence of DM in the mother, and then sub-divided into pregestational and gestational DM groups. Results showed significant associations between maternal diabetes and occurrence of macrosomia, pre-term delivery and less than optimal one-minute Apgar scores. The pre-gestational DM group had significantly more occurrences of macrosomia, pre-term birth, less than optimal Apgar scores, occurrence of complications of labor and/or delivery and occurrence of congenital anomalies than the gestational DM group.
糖尿病(DM)在西弗吉尼亚州是一个严重的问题。孕期糖尿病与多种不良后果相关。本研究检验了以下假设:孕期患有糖尿病的女性比未患糖尿病的女性会有更多不良围产期结局,且孕前糖尿病女性比妊娠期糖尿病女性会有更多不良围产期结局。研究人群包括2001年和2002年参加西弗吉尼亚医疗补助计划的14583名母亲。根据母亲是否患有糖尿病对人群进行划分,然后再细分为孕前糖尿病组和妊娠期糖尿病组。结果显示,母亲糖尿病与巨大儿、早产以及1分钟阿氏评分不理想之间存在显著关联。孕前糖尿病组比妊娠期糖尿病组出现巨大儿、早产、阿氏评分不理想、分娩并发症以及先天性异常的情况明显更多。