Zang Hongmin, Liu Yiheng, Chen Junchang, Wang Kunzheng
Department of Orthopedics, Second Hospital of Xi'an Jiaotong University, Xi'an 710004, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2006 Apr;23(2):366-9.
This study was conducted to find perfect temperature sintered bone as carrier of bone morphogenetic protein (BMP). The different temperature active sintered bones, which were made up of calcine bone and bone morphogenetic protein, were implanted into the defects of rabbit radius. Compared with the sintered bone of 600 degrees C, the sintered bone of 900 degrees C and 1200 degrees C could induce more pieces of bone formation and be replaced by new bone. There were more pieces of new bone formation in sintered bone of 900 degrees C and 1200 degrees C than those in sintered bone of 600 degrees C (P<0.05). There was no difference between the sintered bone of 900 degrees C and 1 200 degrees C (P>0.05). In comparison with the sintered bone of 600 degrees C and 1200 degrees C, the sintered bone of 900 degrees C may be the choicest carrier of bone morphogenetic protein.
本研究旨在寻找理想温度的烧结骨作为骨形态发生蛋白（BMP）的载体。将由煅烧骨和骨形态发生蛋白制成的不同温度活性烧结骨植入兔桡骨缺损处。与600℃的烧结骨相比，900℃和1200℃的烧结骨能诱导更多的骨形成且被新骨替代。900℃和1200℃烧结骨中的新骨形成片数多于600℃烧结骨（P<0.05）。900℃和1200℃的烧结骨之间无差异（P>0.05）。与600℃和1200℃的烧结骨相比，900℃的烧结骨可能是骨形态发生蛋白的最佳载体。
