Yu Hongjie, Jing Huaiqi, Chen Zhihai, Zheng Han, Zhu Xiaoping, Wang Hua, Wang Shiwen, Liu Lunguang, Zu Rongqiang, Luo Longze, Xiang Nijuan, Liu Honglu, Liu Xuecheng, Shu Yuelong, Lee Shui Shan, Chuang Shuk Kwan, Wang Yu, Xu Jianguo, Yang Weizhong
Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China.
Emerg Infect Dis. 2006 Jun;12(6):914-20. doi: 10.3201/eid1206.051194.
From mid-July to the end of August 2005, a total of 215 cases of human Streptococcus suis infections, 66 of which were laboratory confirmed, were reported in Sichuan, China. All infections occurred in backyard farmers who were directly exposed to infection during the slaughtering process of pigs that had died of unknown causes or been killed for food because they were ill. Sixty-one (28%) of the farmers had streptococcal toxic shock syndrome; 38 (62%) of them died. The other illnesses reported were sepsis (24%) and meningitis (48%) or both. All isolates tested positive for genes for tuf, species-specific 16S rRNA, cps2J, mrp, ef, and sly. A single strain of S. suis caused the outbreak, as shown by the identification of a single ribotype. The high death ratio was of concern; prohibiting backyard slaughtering ended the outbreak.
2005年7月中旬至8月底,中国四川省共报告215例人感染猪链球菌病例,其中66例经实验室确诊。所有感染均发生在散养户中,这些人在宰杀死因不明或因病被宰杀以供食用的猪的过程中直接接触到感染源。61名(28%)养殖户患有链球菌中毒性休克综合征,其中38名(62%)死亡。报告的其他病症为败血症(24%)和脑膜炎(48%)或两者皆有。所有分离株的tuf、种特异性16S rRNA、cps2J、mrp、ef和sly基因检测均呈阳性。单一核糖体分型的鉴定表明,此次疫情由单一株猪链球菌引起。高死亡率令人担忧;禁止散养户宰杀生猪后,疫情得以结束。