Solaiman Daniel K Y, Ashby Richard D, Foglia Thomas A, Marmer William N
Fats, Oils and Animal Coproducts Research Unit, Eastern Regional Research Center, Agricultural Research Service, U.S. Department of Agriculture, 600 East Mermaid Lane, Wyndmoor, PA 19038, USA.
Appl Microbiol Biotechnol. 2006 Aug;71(6):783-9. doi: 10.1007/s00253-006-0451-1. Epub 2006 May 18.
Aside from their importance to the survival and general welfare of mankind, agriculture and its related industries produce large quantities of feedstocks and coproducts that can be used as inexpensive substrates for fermentative processes. Successful adoption of these materials into commercial processes could further the realization of a biorefinery industry based on agriculturally derived feedstocks. One potential concept is the production of poly(hydroxyalkanoate) (PHA) polymers, a family of microbial biopolyesters with a myriad of possible monomeric compositions and performance properties. The economics for the fermentative production of PHA could benefit from the use of low-cost agricultural feedstocks and coproducts. This mini-review provides a brief survey of research performed in this area, with specific emphasis on studies describing the utilization of intact triacylglycerols (vegetable oils and animal fats), dairy whey, molasses, and meat-and-bone meal as substrates in the microbial synthesis of PHA polymers.
除了对人类生存和总体福祉至关重要外，农业及其相关产业还生产大量的原料和副产品，这些可作为发酵过程的廉价底物。成功将这些材料应用于商业过程可推动基于农业衍生原料的生物精炼产业的实现。一个潜在的概念是生产聚羟基脂肪酸酯（PHA）聚合物，这是一类微生物生物聚酯，具有无数种可能的单体组成和性能特性。PHA发酵生产的经济性可受益于使用低成本的农业原料和副产品。本综述简要概述了该领域的研究，特别强调了描述将完整的三酰甘油（植物油和动物脂肪）、乳清、糖蜜以及肉骨粉用作PHA聚合物微生物合成底物的研究。
