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三种市售贯叶连翘制剂对小鼠的药理活性。

Pharmacological activity of three commercial Hypericum perforatum preparations in mice.

作者信息

Jean D, Pouligon M, Henriot A C

机构信息

Institut des Substances Végétales, 283 rue de la Chaussade, 63270 Vic-le-Comte, France.

出版信息

Phytother Res. 2006 Aug;20(8):653-4. doi: 10.1002/ptr.1924.

DOI:10.1002/ptr.1924
PMID:16708407
Abstract

St John's Wort (Hypericum perforatum) is the main herbal species used to treat depression. The products available on the pharmaceutical and dietary supplement markets are obtained by a variety of preparation processes and their pharmacological effects may differ significantly. The purpose of this study therefore was to investigate the effect of different St John's Wort commercial preparations available on the French market. Only one preparation gave significant results in the forced swimming test.

摘要

圣约翰草(贯叶连翘)是用于治疗抑郁症的主要草药品种。制药和膳食补充剂市场上的产品通过多种制备工艺获得,其药理作用可能有显著差异。因此,本研究的目的是调查法国市场上不同的圣约翰草商业制剂的效果。在强迫游泳试验中,只有一种制剂产生了显著效果。

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Pharmacological activity of three commercial Hypericum perforatum preparations in mice.三种市售贯叶连翘制剂对小鼠的药理活性。
Phytother Res. 2006 Aug;20(8):653-4. doi: 10.1002/ptr.1924.
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Effects of oral administration of extracts of Hypericum perforatum (St John's wort) on brain serotonin transporter, serotonin uptake and behaviour in mice.口服贯叶连翘提取物对小鼠脑血清素转运体、血清素摄取及行为的影响。
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Pharmacological studies in an herbal drug combination of St. John's Wort (Hypericum perforatum) and passion flower (Passiflora incarnata): in vitro and in vivo evidence of synergy between Hypericum and Passiflora in antidepressant pharmacological models.圣约翰草(贯叶连翘)和西番莲(西番莲)草药组合的药理学研究:在抗抑郁药理学模型中贯叶连翘和西番莲之间协同作用的体外和体内证据。
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Rutin is essential for the antidepressant activity of Hypericum perforatum extracts in the forced swimming test.在强迫游泳试验中,芦丁对于贯叶连翘提取物的抗抑郁活性至关重要。
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The antidepressant activity of Hypericum perforatum L. measured by two experimental methods on mice.通过两种实验方法对小鼠测定贯叶连翘的抗抑郁活性。
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Effect of St John's wort (Hypericum perforatum) on cytochrome P-450 activity in perfused rat liver.圣约翰草(贯叶连翘)对灌注大鼠肝脏中细胞色素P-450活性的影响。
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Preserved pharmacological activity of hepatocytes-treated extracts of valerian and St. John's wort.缬草和圣约翰草经肝细胞处理的提取物的药理活性得以保留。
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