Amerio Paolo, Innocente Carmela, Feliciani Claudio, Angelucci Domenico, Gambi Domenico, Tulli Antonio
Dermatology Dept., University G. D'Annunzio, Chieti, Italy.
Eur J Dermatol. 2006 May-Jun;16(3):281-3.
Drug-induced lupus is a disease, inducible by several drugs, that shares symptoms and laboratory characteristics with idiopathic lupus erythematosus. We report a case of carbamazepine-induced cutaneous lupus erythematosus which developed after 5 years of treatment in a patient who was on this medication because of an epileptic crisis after cranial trauma. Carbamazepine is a medication rarely implicated in drug-induced cutaneous lupus, moreover there are very few reports of such long periods between the start of therapy and the presentation of the clinical symptoms. We describe this case to emphasize the possibility of cutaneous lupus induction by carbamazepine even after many years of therapy.
药物性狼疮是一种可由多种药物诱发的疾病，它与特发性红斑狼疮具有相同的症状和实验室特征。我们报告了一例卡马西平诱发的皮肤性红斑狼疮病例，该病例发生在一名因颅脑外伤后癫痫发作而服用此药治疗5年的患者身上。卡马西平是一种很少引发药物性皮肤狼疮的药物，而且从治疗开始到出现临床症状间隔如此长的时间的报告非常少。我们描述这个病例是为了强调即使经过多年治疗，卡马西平仍有可能诱发皮肤狼疮。
