An ongoing pregnancy after frozen thawed embryo transfer in a patient with Klinefelter's syndrome.

BACKGROUND

Pregnancy following frozen thawed embryo transfer in a patient with nonmosaic Klinefelter's syndrome is extremely rare. A healthy ongoing pregnancy achieved with frozen thawed embryo transfer in a patient with nonmosaic Klinefelter's syndrome was described.

METHOD

A case report from a tertiary center for assisted reproductive technologies. A 34-year-old man with azoospermia and nonmosaic Klinefelter's syndrome and his 26-year-old wife presented with primary infertility of 8 years' duration. Frozen thawed embryo transfer following intracytoplasmic sperm injection using surgically retrieved spermatozoa was performed.

RESULTS

A healthy ongoing pregnancy with a normal 46,XY karyotype was achieved with day 3 frozen thawed embryo transfer.

CONCLUSION

Frozen thawed embryo transfer may be a viable option to achieve pregnancy in patients with Klinefelter's syndrome.