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[0.1% 阿氯米松丙酸酯与0.05% 二丙酸倍他米松在小儿包茎患儿中的疗效比较]

[Comparative effectiveness of 0.1% metilprednisolone aceponate and 0.05% betamethasone dipropionate among children with nonretractable prepuce].

作者信息

Ceballos-González Sergio, Torres-Cantero César, Trujillo-Hernández Benjamín, Muñiz Jesús, Huerta Miguel, Trujillo Xochitl, Vásquez Clemente

机构信息

Servicio de Urología, Hospital General de Zona y Medicina Familiar No. 1, IMSS, Colima, Colima, México.

出版信息

Gac Med Mex. 2006 Mar-Apr;142(2):121-4.

PMID:16711546
Abstract

OBJECTIVE

To compare clinical improvement between treatment with metilprednisolone aceponate vs. betamethasone dipropionate among children with nonretractable prepuce.

MATERIAL AND METHODS

Between August 2001 and November 2002, we carried out a double blind and controlled clinical trial in 34 children with a diagnosis of nonretracable prepuce. Children were randomly assigned to one of the following groups and topical treatment was administered: Group A; metilprednisolone aceponate 0. I 1% and Group B; betamethasone dipropionate 0.05%.

RESULTS

Improvement was noted in 88.2% of our sample studied; (n= 15) children from group A and 76.4% (n= 13) childrenfrom group B; however, we did not observe a significant difference when comparing percentages between the two groups (chi2 = 0.2; p = 0.6).

CONCLUSIONS

The percentage of clinical improvement was similar between the two groups of topical steroid treatment administered.

摘要

目的

比较用醋丙甲泼尼龙与二丙酸倍他米松治疗小儿包茎的临床效果。

材料与方法

2001年8月至2002年11月,我们对34例诊断为包茎的患儿进行了一项双盲对照临床试验。将患儿随机分为以下组并给予局部治疗:A组,0.1%醋丙甲泼尼龙;B组,0.05%二丙酸倍他米松。

结果

在我们研究的样本中,88.2%(n = 15)的A组患儿和76.4%(n = 13)的B组患儿有改善;然而,比较两组的百分比时,我们未观察到显著差异(χ² = 0.2;p = 0.6)。

结论

两组局部用类固醇治疗的临床改善百分比相似。

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