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类固醇给药使高安动脉炎患者左主干病变消退

Regression of the left main trunk lesion by steroid administration in Takayasu's aortitis.

作者信息

Iga K, Gohma I, Hori K

机构信息

Department of Cardiology, Tenri Hospital, Japan.

出版信息

Chest. 1991 Feb;99(2):508-10. doi: 10.1378/chest.99.2.508.

DOI:10.1378/chest.99.2.508
PMID:1671213
Abstract

A 62-year-old man with unstable angina due to severe narrowing of the left main trunk (LMT) was examined. Emergency bypass surgery was performed with an internal mammary artery graft, instead of a saphenous vein graft, because of the thickened, edematous ascending aorta. Postoperative coronary angiography showed the lesion of the LMT markedly regressing. Presumably, this stenotic lesion of the LMT was caused by active aortitis and was partially reversible by steroid administration both during and after surgery. Steroid therapy can be added to the list of treatments for cases of LMT disease associated with Takayasu's aortitis, if signs of active inflammation are present.

摘要

一名62岁男性因左主干(LMT)严重狭窄导致不稳定型心绞痛接受检查。由于升主动脉增厚、水肿,急诊搭桥手术采用了乳内动脉移植,而非大隐静脉移植。术后冠状动脉造影显示LMT病变明显消退。据推测,LMT的这种狭窄病变是由活动性主动脉炎引起的,在手术期间和术后通过使用类固醇均可部分逆转。如果存在活动性炎症迹象,类固醇治疗可被列入与高安动脉炎相关的LMT疾病病例的治疗方法清单中。

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引用本文的文献

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Intern Med. 2024 Oct 1;63(19):2641-2646. doi: 10.2169/internalmedicine.3032-23. Epub 2024 Feb 26.
2
Clinical characteristics and outcomes in patients with Takayasu arteritis coexisting with myocardial ischemia and neurological symptoms: A multicenter, long-term, follow-up study.高安动脉炎合并心肌缺血和神经症状患者的临床特征及预后:一项多中心、长期随访研究
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3
Acute myocardial infarction with left main coronary artery ostial negative remodelling as the first manifestation of Takayasu arteritis: a case report.
以左主干冠状动脉开口负性重构为首发表现的 Takayasu 动脉炎致急性心肌梗死 1 例报告。
BMC Cardiovasc Disord. 2021 Nov 22;21(1):560. doi: 10.1186/s12872-021-02376-w.
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High-sensitivity C-reactive protein predicts adverse cardiovascular events in patients with Takayasu arteritis with coronary artery involvement.高敏C反应蛋白可预测累及冠状动脉的大动脉炎患者发生不良心血管事件。
Clin Rheumatol. 2016 Mar;35(3):679-84. doi: 10.1007/s10067-015-2873-6. Epub 2015 Feb 10.
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Takayasu's arteritis: management of left main stem stenosis.高安动脉炎:左主干狭窄的管理
Heart. 2003 Mar;89(3):e9. doi: 10.1136/heart.89.3.e9.
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Regression of left main coronary ostium stenosis after surgical revascularization and steroid therapy.
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Cardiac catheter complications related to left main stem disease.与左主干疾病相关的心脏导管并发症。
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