Vitali Federica, Fonte Giuseppina, Saija Antonella, Tita Beatrice
Department of Human Physiology and Pharmacology, University of Rome La Sapienza, Piazzale A. Moro 5, 00185 Rome, Italy.
J Ethnopharmacol. 2006 Oct 11;107(3):342-8. doi: 10.1016/j.jep.2006.03.025. Epub 2006 Apr 6.
Ethanol extracts of the fresh aerial parts of various Epilobium species were tested to elucidate the mechanism of their gastrointestinal activity in animals. The methods of charcoal meal, castor oil-induced diarrhoea, and enteropooling assay were used to evaluate their effect on mouse gut at various dose levels. The extracts were found to have a significant activity in all models. Moreover, the extracts resulted to possess very little toxicity. Thus, it can be concluded that Epilobium possesses anti-diarrhoeal, anti-motility, and anti-secretory activities and can prove beneficial in the treatment of gastrointestinal disorders.
对各种柳叶菜属植物新鲜地上部分的乙醇提取物进行了测试，以阐明其在动物体内的胃肠道活性机制。采用炭末法、蓖麻油致泻法和肠积液试验法，在不同剂量水平下评估它们对小鼠肠道的影响。结果发现提取物在所有模型中均具有显著活性。此外，提取物的毒性非常小。因此，可以得出结论，柳叶菜属植物具有止泻、抗蠕动和抗分泌活性，在治疗胃肠道疾病方面可能有益。
