Wiesler Ethan R, Chloros George D, Cartwright Michael S, Smith Beth P, Rushing Julia, Walker Francis O
Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.
J Hand Surg Am. 2006 May-Jun;31(5):726-32. doi: 10.1016/j.jhsa.2006.01.020.
Traditional evaluation of suspected carpal tunnel syndrome (CTS) involves a thorough history, physical examination, and nerve conduction velocity studies (NCS). Ultrasound is used widely in Europe and has gained acceptance in the United States in the diagnosis of various musculoskeletal disorders. The purpose of this study was to document the ultrasonographic measurement difference in median nerve size between patients with CTS and controls and to correlate these findings with NCS findings, thereby allowing us to test the validity of ultrasound as a diagnostic modality for CTS.
Forty-four wrists in 26 CTS patients and 86 wrists in 43 asymptomatic volunteers were imaged using a real-time ultrasound scanner with a 12/5 MHz linear-array transducer. The cross-sectional area of the median nerve was measured at the level of the distal wrist crease in both CTS patients and controls. All CTS patients had NCS. The ultrasonographic median nerve area was compared for the 2 groups and correlation analysis between ultrasonographic nerve sizes and NCS findings was performed.
The average cross-sectional area of the median nerve at the distal wrist crease was 9 mm(2) in asymptomatic volunteers and 14 mm(2) in CTS patients. For the CTS patients the Pearson correlation coefficient between ultrasound nerve measurement and NCS values was 0.37, suggesting that higher values of ultrasound measurements are associated with abnormal NCS findings.
Our results indicate that high-resolution ultrasound is informative in the evaluation of CTS and shows enlargement of the median nerve at the distal wrist crease in symptomatic patients. Therefore it is a reliable modality for imaging the wrist in patients with CTS. In addition ultrasound is well tolerated and safe.
TYPE OF STUDY/LEVEL OF EVIDENCE: Diagnostic, Level I.
对疑似腕管综合征(CTS)的传统评估包括详细的病史、体格检查及神经传导速度研究(NCS)。超声在欧洲被广泛应用,在美国也已被认可用于诊断各种肌肉骨骼疾病。本研究的目的是记录CTS患者与对照组之间正中神经大小的超声测量差异,并将这些结果与NCS结果相关联,从而检验超声作为CTS诊断方法的有效性。
使用配备12/5 MHz线性阵列换能器的实时超声扫描仪,对26例CTS患者的44只手腕及43名无症状志愿者的86只手腕进行成像。在CTS患者和对照组中,均于腕部远端横纹水平测量正中神经的横截面积。所有CTS患者均进行了NCS检查。比较两组的超声正中神经面积,并对超声神经大小与NCS结果进行相关性分析。
无症状志愿者腕部远端横纹处正中神经的平均横截面积为9 mm²,CTS患者为14 mm²。对于CTS患者,超声神经测量值与NCS值之间的Pearson相关系数为0.37,表明超声测量值越高与NCS异常结果相关。
我们的结果表明,高分辨率超声在CTS评估中具有参考价值,且显示有症状患者腕部远端横纹处正中神经增粗。因此,它是CTS患者手腕成像的可靠方法。此外,超声耐受性良好且安全。
研究类型/证据水平:诊断性研究,I级。