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节后交感神经缩窄处的两种群体或颗粒小泡。

Two populations or granular vesicles in constricted post-ganglionic sympathetic nerves.

作者信息

Tomlinson D R

出版信息

J Physiol. 1975 Mar;245(3):727-35. doi: 10.1113/jphysiol.1975.sp010871.

DOI:10.1113/jphysiol.1975.sp010871
PMID:167158
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1330815/
Abstract
  1. A comparative study has been made of the effects of different fixatives on the ultrastructural appearance of granular vesicles accumulated against a constriction in cat hypogastric nerves. 2. After fixation in either osmium tetroxide or in glutaraldehyde followed by post-osmication accumulations of large granular vesicles (65-90 nm in diameter) were observed in profiles of swollen axons. 3. Fixation in acrolein and sodium dichromate revealed a second population of small granular vesicles (mostly 30-50 nm in diameter) in addition to the large vesicles seen after the other fixatives. 4. In reserpinized cats the small granular vesicles were absent. The large granular vesicles were much less numerous, irrespective of the fixative used. 5. It is suggested that either the small vesicles occur in normal noradrenergic axons but are only revealed by catecholamine-sensitive fixatives or they occur as a result of constricting the nerve trunk. Evidence for and against these possibilities is discussed.
摘要
  1. 已对不同固定剂对猫腹下神经中紧靠狭窄处积聚的颗粒小泡超微结构外观的影响进行了比较研究。2. 用四氧化锇或戊二醛固定后再进行后固定，在肿胀轴突的切片中观察到直径为65 - 90纳米的大颗粒小泡的积聚。3. 用丙烯醛和重铬酸钠固定后，除了其他固定剂处理后可见的大颗粒小泡外，还发现了第二批小颗粒小泡（大多直径为30 - 50纳米）。4. 在利血平化的猫中，小颗粒小泡不存在。无论使用何种固定剂，大颗粒小泡的数量都少得多。5. 有人提出，要么小泡存在于正常的去甲肾上腺素能轴突中，但仅由对儿茶酚胺敏感的固定剂显示出来，要么它们是由于压迫神经干而产生的。讨论了支持和反对这些可能性的证据。
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1fd/1330815/89f7c68e2ad7/jphysiol00908-0238-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1fd/1330815/56a9a9186fcb/jphysiol00908-0236-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1fd/1330815/9831c1b79789/jphysiol00908-0237-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1fd/1330815/89f7c68e2ad7/jphysiol00908-0238-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1fd/1330815/56a9a9186fcb/jphysiol00908-0236-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1fd/1330815/9831c1b79789/jphysiol00908-0237-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1fd/1330815/89f7c68e2ad7/jphysiol00908-0238-a.jpg

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Two populations or granular vesicles in constricted post-ganglionic sympathetic nerves.节后交感神经缩窄处的两种群体或颗粒小泡。
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Markers of axonal injury in post mortem human brain.人类死后大脑中轴突损伤的标志物。
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3
Ultracytochemical identification of catecholamine-containing vesicles in the ligated sciatic nerve of the rat. Comparison with sympathetic nerve terminals.大鼠结扎坐骨神经中含儿茶酚胺囊泡的超细胞化学鉴定。与交感神经末梢的比较。

本文引用的文献

1
A study of fixation for electron microscopy.电子显微镜固定研究。
J Exp Med. 1952 Mar;95(3):285-98. doi: 10.1084/jem.95.3.285.
2
AN IMPROVED METHOD FOR FLUORIMETRIC DETERMINATION OF SMALL AMOUNTS OF ADRENALINE AND NORADRENALINE IN PLASMA AND TISSUES.一种改进的血浆和组织中微量肾上腺素和去甲肾上腺素荧光测定方法。
Acta Physiol Scand. 1963 Nov;59:242-54. doi: 10.1111/j.1748-1716.1963.tb02739.x.
3
The use of lead citrate at high pH as an electron-opaque stain in electron microscopy.在电子显微镜检查中，将高pH值的柠檬酸铅用作电子不透明染色剂。
Cell Tissue Res. 1980;209(3):433-54. doi: 10.1007/BF00234757.
4
Mechanism of uptake and retrograde axonal transport of noradrenaline in sympathetic neurons in culture: reserpine-resistant large dense-core vesicles as transport vehicles.培养的交感神经元中去甲肾上腺素的摄取及逆行轴突运输机制：作为运输载体的利血平抗性大致密核心囊泡
J Cell Biol. 1983 Jun;96(6):1538-47. doi: 10.1083/jcb.96.6.1538.
5
Endocrine secretory granules and neuronal synaptic vesicles have three integral membrane proteins in common.内分泌分泌颗粒和神经元突触小泡共有三种整合膜蛋白。
J Cell Biol. 1988 Jan;106(1):51-9. doi: 10.1083/jcb.106.1.51.
6
The effect of tetrabenazine on the accumulation of noradrenaline in constricted postganglionic sympathetic nerves in vitro.丁苯那嗪对体外收缩的节后交感神经中去甲肾上腺素蓄积的影响。
Cell Tissue Res. 1975 Jul 23;160(4):495-504. doi: 10.1007/BF00225766.
7
The involvement of noradrenergic nerves in the cardiovascular reflex responses to lower body negative pressure in the anaesthetised rabbit.
Pflugers Arch. 1976 Sep 3;365(1):89-94. doi: 10.1007/BF00583632.
8
Selective noradrenergic denervation of the heart following intravenous injections of vinblastine or vincristine.静脉注射长春碱或长春新碱后心脏的选择性去甲肾上腺素能神经支配缺失
Naunyn Schmiedebergs Arch Pharmacol. 1976 May;293(2):175-82. doi: 10.1007/BF00499224.
9
The mode of action of tetrabenazine on peripheral noradrenergic nerves.丁苯那嗪对外周去甲肾上腺素能神经的作用方式。
Br J Pharmacol. 1977 Nov;61(3):339-44. doi: 10.1111/j.1476-5381.1977.tb08425.x.
J Cell Biol. 1963 Apr;17(1):208-12. doi: 10.1083/jcb.17.1.208.
4
Fluorescence microscopy and electron microscopy of adrenergic nerves after constriction at two points.两点缩窄后肾上腺素能神经的荧光显微镜检查和电子显微镜检查
J R Microsc Soc. 1967;87(2):277-94.
5
The effects of iproniazid and reserpine on the accumulation of granular vesicles and noradrenaline in constricted adrenergic nerves.异烟肼和利血平对缩窄的肾上腺素能神经中颗粒小泡和去甲肾上腺素积累的影响。
Br J Pharmacol. 1969 Sep;37(1):10-8. doi: 10.1111/j.1476-5381.1969.tb09516.x.
6
Distribution of granular vesicles in normal and constricted sympathetic neurones.正常和收缩的交感神经元中颗粒小泡的分布
J Physiol. 1969 Oct;204(3):583-92. doi: 10.1113/jphysiol.1969.sp008933.
7
The storage of endogenous noradrenaline in sympathetic nerve terminals.内源性去甲肾上腺素在交感神经末梢中的储存。
J Physiol. 1971 May;215(1):163-79. doi: 10.1113/jphysiol.1971.sp009463.
8
Distribution of noradrenaline storing particles in peripheral adrenergic neurons as revealed by electron microscopy.通过电子显微镜揭示的外周肾上腺素能神经元中去甲肾上腺素储存颗粒的分布。
Acta Physiol Scand. 1969 Aug;76(4):427-40. doi: 10.1111/j.1748-1716.1969.tb04488.x.
9
On the origin of small adrenergic storage vesicles: evidence for local formation in nerve endings after chronic reserpine treatment.论小肾上腺素能储存囊泡的起源：慢性利血平治疗后神经末梢局部形成的证据。
Experientia. 1973 May 15;29(5):580-2. doi: 10.1007/BF01926677.
10
The innervation of the frog's heart. 3. Electronmicroscopy of the autonomic nerve fibres and their vesicles.
Proc R Soc Lond B Biol Sci. 1970 Oct 13;176(1042):63-8. doi: 10.1098/rspb.1970.0034.