Hoffmann Jörg, Ihrig Andreas, Hoth Sebastian, Triebig Gerhard
Institute and Outpatient Clinic for Occupational and Social Medicine, University Hospital Heidelberg, Vosstrasse 2, 69115 Heidelberg, Germany.
Ind Health. 2006 Apr;44(2):283-6. doi: 10.2486/indhealth.44.283.
We conducted this study to examine, whether occupational styrene exposures are associated with reduced hearing ability.
The auditory function was investigated by pure tone audiometry and registration of transitory evoked otoacoustic emissions (TEOAE) in 32 workers of a fibre-reinforced plastic boat building factory. Sixteen subjects were laminators (mean age: 41 yr (SD: 8)) and therefore regularly exposed to styrene with mean duration of exposure to styrene of 7.5 yr (SD 5.0). The tests were applied to a reference group of 16 workers (mean age: 39 yr (SD: 8)) who were not directly exposed to styrene but had a similar noise exposure.
A few and isolated correlations between the parameters of hearing acuity and exposure indices, such as current internal styrene exposures (sum of MA and PGA) and duration of styrene exposure, were statistically significant, but no consistent association was found.
The results of this study do not support the assumption of an ototoxic effect of chronic styrene exposure in workers.
我们开展本研究以检验职业性苯乙烯暴露是否与听力下降有关。
对一家纤维增强塑料造船厂的32名工人进行了纯音听力测定和瞬态诱发耳声发射(TEOAE)记录,以研究其听觉功能。16名受试者为层压机操作工(平均年龄:41岁(标准差:8岁)),因此经常接触苯乙烯,平均接触苯乙烯时间为7.5年(标准差5.0年)。对16名未直接接触苯乙烯但有类似噪声暴露的工人组成的参照组进行了测试(平均年龄:39岁(标准差:8岁))。
听力敏锐度参数与暴露指标之间存在一些孤立的相关性,如当前体内苯乙烯暴露量(MA和PGA之和)和苯乙烯暴露持续时间,具有统计学意义,但未发现一致的关联。
本研究结果不支持工人慢性苯乙烯暴露具有耳毒性作用这一假设。