病例报告：基因分型在经典猪瘟（CSF）流行病学追踪中的意义。

Case report: the significance of genotyping for the epidemiological tracing of classical swine fever (CSF).

作者信息

Depner K R, Strebelow G, Staubach Ch, Kramer M, Teuffert J, Bötcher L, Hoffmann B, Beer M, Greiser-Wilke I, Mettenleiter T

机构信息

Friedrich-Loeffler-lnstitut, Insel Riems-Greifswald, Germany.

出版信息

Dtsch Tierarztl Wochenschr. 2006 Apr;113(4):159-62.

PMID:16716053

Abstract

In Germany, eleven outbreaks of CSF in domestic pig holdings were reported in 2002. They occurred exclusively in regions where CSF virus circulated in the wild boar population. In ten cases the phylogenetic analysis revealed that the isolates from domestic pigs and wild boar had identical sequences in the 5' non-translated region (5'NTR). However, in one case a subtype was isolated which was slightly different from the virus subtype found in the wild boar population of that region. This case is decribed in detail. The epidemiological significance of different diagnostic methods is discussed, in particular the genetic typing of CSF virus isolates.

摘要

2002年，德国报告了11起家猪养殖场猪瘟暴发事件。这些事件仅发生在野猪群体中传播猪瘟病毒的地区。在10起事件中，系统发育分析显示，家猪和野猪的分离株在5'非翻译区（5'NTR）具有相同序列。然而，在1起事件中分离出了一种亚型，该亚型与该地区野猪群体中发现的病毒亚型略有不同。详细描述了这起事件。讨论了不同诊断方法的流行病学意义，特别是猪瘟病毒分离株的基因分型。