Wickbom Anna, Lindqvist Magnus, Bohr Johan, Ung Kjell-Arne, Bergman Jan, Eriksson Sune, Tysk Curt
Division of Gastroenterology, Department of Medicine, Orebro University Hospital, Orebro, Sweden.
Scand J Gastroenterol. 2006 Jun;41(6):726-9. doi: 10.1080/00365520500453473.
In general, the colonic mucosa is macroscopically normal in collagenous colitis, although minor, non-specific abnormalities may be found. Significant endoscopic abnormalities, "mucosal tears" representing longitudinal mucosal lacerations, have been reported in a few patients with collagenous colitis. We report the cases of three women with collagenous colitis and mucosal tears detected at the index colonoscopy in order to illustrate the endoscopic characteristics and review the literature. Including the present cases, a total of 12 patients with mucosal tears and collagenous colitis have been reported. In 10 patients, the mucosal lacerations involved the ascending or the transverse colon. Three of the 12 patients had a colonic perforation immediately after the colonoscopy. The colonoscopist should be aware that the risk of perforation is likely to be increased when mucosal tears are present.
一般来说，胶原性结肠炎患者的结肠黏膜在宏观上是正常的，不过可能会发现一些轻微的非特异性异常。有少数胶原性结肠炎患者报告存在显著的内镜异常，即代表纵向黏膜撕裂的“黏膜撕裂伤”。我们报告3例在首次结肠镜检查时发现有胶原性结肠炎及黏膜撕裂伤的女性病例，以阐述内镜特征并回顾相关文献。包括本病例在内，总共报告了12例有黏膜撕裂伤的胶原性结肠炎患者。其中10例患者的黏膜撕裂累及升结肠或横结肠。12例患者中有3例在结肠镜检查后立即发生了结肠穿孔。结肠镜检查者应意识到，存在黏膜撕裂伤时穿孔风险可能会增加。
