NETGEN：生成具有二倍体杂种的系统发育网络
NETGEN: generating phylogenetic networks with diploid hybrids.
作者信息
Morin M M, Moret B M E
机构信息
Department of Computer Science, University of New Mexico, Albuquerque, NM, USA.
出版信息
Bioinformatics. 2006 Aug 1;22(15):1921-3. doi: 10.1093/bioinformatics/btl191. Epub 2006 May 22.
SUMMARY
NetGen is an event-driven simulator that creates phylogenetic networks by extending the birth-death model to include diploid hybridizations. DNA sequences are evolved in conjunction with the topology, enabling hybridization decisions to be based on contemporary evolutionary distances. NetGen supports variable rate lineages, root sequence specification, outgroup generation and many other options. This note describes the NetGen application and proposes an extension of the Newick format to accommodate phylogenetic networks.
AVAILABILITY
NetGen is written in C and is available in source form at http://www.phylo.unm.edu/~morin/.
摘要
NetGen是一个事件驱动的模拟器，它通过扩展生死模型以纳入二倍体杂交来创建系统发育网络。DNA序列与拓扑结构一起进化，使得杂交决策能够基于当代进化距离。NetGen支持可变速率谱系、根序列指定、外类群生成以及许多其他选项。本说明描述了NetGen应用程序，并提出了对Newick格式的扩展以适应系统发育网络。
可用性
NetGen用C编写，其源代码可在http://www.phylo.unm.edu/~morin/获取。
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