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大肠杆菌中的铁转运:仍有未尽之言与未竟之事。

Iron transport in Escherichia coli: all has not been said and done.

作者信息

Grass Gregor

机构信息

Institut für Mikrobiologie, Martin-Luther-Universität Halle, Kurt-Mothes-Str. 3, 06120, Halle, Germany.

出版信息

Biometals. 2006 Apr;19(2):159-72. doi: 10.1007/s10534-005-4341-2.

DOI:10.1007/s10534-005-4341-2
PMID:16718601
Abstract

During recent years new systems involved in iron transport were identified in the old workhorse Escherichia coli (and in other enterobacteria). This came as a bit of a surprise because one might think transport of this essential trace element was already thoroughly studied. Moreover, it appears that iron homeostasis consists not only of uptake but also of efflux of this potentially toxic redox-active metal. New findings in E. coli will be discussed and compared to the situation in other bacteria.

摘要

近年来,在经典的实验菌株大肠杆菌(以及其他肠道细菌)中发现了参与铁转运的新系统。这有点令人惊讶,因为人们可能认为这种必需微量元素的转运已经得到了充分研究。此外,铁稳态似乎不仅包括这种潜在有毒的氧化还原活性金属的摄取,还包括其外排。本文将讨论大肠杆菌中的新发现,并与其他细菌的情况进行比较。

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