Rosa-Núñez Elena, Echavarri-Erasun Carlos, Armas Alejandro M, Escudero Viviana, Poza-Carrión César, Rubio Luis M, González-Guerrero Manuel
Centro de Biotecnología y Genómica de Plantas (UPM-INIA/CSIC), Campus de Montegancedo UPM, Crta. M-40 km 38, 28223 Madrid, Spain.
Escuela Técnica de Ingeniería Agraria, Alimentaria, y de Biosistemas, Universidad Politécnica de Madrid, Avda. Puerta de Hierro, 2, 28040 Madrid, Spain.
Biology (Basel). 2023 Nov 12;12(11):1423. doi: 10.3390/biology12111423.
Iron is an essential nutrient for all life forms. Specialized mechanisms exist in bacteria to ensure iron uptake and its delivery to key enzymes within the cell, while preventing toxicity. Iron uptake and exchange networks must adapt to the different environmental conditions, particularly those that require the biosynthesis of multiple iron proteins, such as nitrogen fixation. In this review, we outline the mechanisms that the model diazotrophic bacterium uses to ensure iron nutrition and how it adapts Fe metabolism to diazotrophic growth.
铁是所有生命形式必需的营养物质。细菌中存在专门的机制来确保铁的摄取及其向细胞内关键酶的传递，同时防止毒性。铁摄取和交换网络必须适应不同的环境条件，特别是那些需要多种铁蛋白生物合成的条件，如固氮作用。在这篇综述中，我们概述了模式固氮细菌用于确保铁营养的机制，以及它如何使铁代谢适应固氮生长。
