van Dijk J G, Dorresteijn M, Haan J, Ferrari M D
Department of Neurology/Clinical Neurophysiology, Leiden University Hospital, Netherlands.
Lancet. 1991 Mar 2;337(8740):517-8. doi: 10.1016/0140-6736(91)91298-9.
We have attempted to replicate the results of studies on a diagnostic test reported to have 90% sensitivity and 89-96% specificity for migraine. The technique is based on peak-to-peak measurements of fast background electroencephalographic activity during a visual evoked potential (VEP) study. VEP latencies and amplitudes did not differ significantly, and showed substantial overlap, between a group of eight migraine patients and ten age-matched healthy controls. We could not recognise previously described fast activity or measure it objectively by peak-to-peak measurements. We cannot confirm that measurement of fast wave activity in the VEP background is useful in diagnosis of migraine.
我们试图重复一项关于诊断测试的研究结果，该测试据报道对偏头痛具有90%的敏感性和89 - 96%的特异性。该技术基于视觉诱发电位（VEP）研究期间快速背景脑电图活动的峰峰值测量。在一组八名偏头痛患者和十名年龄匹配的健康对照之间，VEP潜伏期和振幅没有显著差异，且有大量重叠。我们无法识别先前描述的快速活动，也无法通过峰峰值测量客观地测量它。我们不能证实VEP背景中快波活动的测量对偏头痛的诊断有用。
