• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

达托霉素、万古霉素和利福平联合治疗复发性、严重的涉及耐甲氧西林金黄色葡萄球菌的骨与人工关节感染。

Combination therapy with daptomycin, vancomycin, and rifampin for recurrent, severe bone and prosthetic joint infections involving methicillin-resistant Staphylococcus aureus.

作者信息

Antony Suresh J

机构信息

Texas Tech University School of Medicine, El Paso 79915, USA.

出版信息

Scand J Infect Dis. 2006;38(4):293-5. doi: 10.1080/00365540500372697.

DOI:10.1080/00365540500372697
PMID:16718933
Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) infections are commonly treated with vancomycin (VAN) or another glycopeptide antibiotic. However, when vancomycin fails or infections recur, there are few other therapeutic options. Presented here are 2 cases where a novel combination of daptomycin, vancomycin, and rifampin resolved recurrent MRSA bone and prosthetic joint functions.

摘要

耐甲氧西林金黄色葡萄球菌（MRSA）感染通常用万古霉素（VAN）或另一种糖肽类抗生素治疗。然而，当万古霉素治疗失败或感染复发时，几乎没有其他治疗选择。本文介绍了2例通过达托霉素、万古霉素和利福平的新型联合用药治愈复发性MRSA骨和人工关节感染的病例。

相似文献

1
Combination therapy with daptomycin, vancomycin, and rifampin for recurrent, severe bone and prosthetic joint infections involving methicillin-resistant Staphylococcus aureus.达托霉素、万古霉素和利福平联合治疗复发性、严重的涉及耐甲氧西林金黄色葡萄球菌的骨与人工关节感染。
Scand J Infect Dis. 2006;38(4):293-5. doi: 10.1080/00365540500372697.
2
Adjunctive rifampin is crucial to optimizing daptomycin efficacy against rabbit prosthetic joint infection due to methicillin-resistant Staphylococcus aureus.由于耐甲氧西林金黄色葡萄球菌，利福平辅助治疗对优化达托霉素治疗兔人工关节感染的疗效至关重要。
Antimicrob Agents Chemother. 2011 Oct;55(10):4589-93. doi: 10.1128/AAC.00675-11. Epub 2011 Aug 8.
3
Successful treatment of daptomycin-nonsusceptible methicillin-resistant Staphylococcus aureus bacteremia with the addition of rifampin to daptomycin.利福平联合达托霉素治疗达托霉素中介耐甲氧西林金黄色葡萄球菌菌血症
Ann Pharmacother. 2010 May;44(5):918-21. doi: 10.1345/aph.1M665. Epub 2010 Mar 30.
4
Efficacy of daptomycin in experimental endocarditis due to methicillin-resistant Staphylococcus aureus.达托霉素对耐甲氧西林金黄色葡萄球菌所致实验性心内膜炎的疗效。
Antimicrob Agents Chemother. 2003 May;47(5):1714-8. doi: 10.1128/AAC.47.5.1714-1718.2003.
5
Efficacy of usual and high doses of daptomycin in combination with rifampin versus alternative therapies in experimental foreign-body infection by methicillin-resistant Staphylococcus aureus.常规剂量和高剂量达托霉素联合利福平与替代疗法治疗耐甲氧西林金黄色葡萄球菌实验性异物感染的疗效比较。
Antimicrob Agents Chemother. 2010 Dec;54(12):5251-6. doi: 10.1128/AAC.00226-10. Epub 2010 Oct 4.
6
Efficacy of daptomycin combined with rifampicin for the treatment of experimental meticillin-resistant Staphylococcus aureus (MRSA) acute osteomyelitis.达托霉素联合利福平治疗实验性耐甲氧西林金黄色葡萄球菌（MRSA）急性骨髓炎的疗效。
Int J Antimicrob Agents. 2010 Dec;36(6):542-4. doi: 10.1016/j.ijantimicag.2010.07.008. Epub 2010 Sep 18.
7
Daptomycin and rifampin for the treatment of methicillin-resistant Staphylococcus aureus septic pulmonary emboli in the absence of endocarditis.达托霉素和利福平治疗耐甲氧西林金黄色葡萄球菌脓毒性肺栓塞，无心内膜炎。
Microb Drug Resist. 2010 Sep;16(3):241-4. doi: 10.1089/mdr.2010.0001.
8
Methicillin-resistant Staphylococcus aureus prosthetic aortic valve endocarditis with paravalvular abscess treated with daptomycin.用达托霉素治疗的耐甲氧西林金黄色葡萄球菌人工主动脉瓣心内膜炎合并瓣周脓肿
Heart Lung. 2005 Jan-Feb;34(1):69-71. doi: 10.1016/j.hrtlng.2004.07.009.
9
Diminished vancomycin and daptomycin susceptibility during prolonged bacteremia with methicillin-resistant Staphylococcus aureus.耐甲氧西林金黄色葡萄球菌长期菌血症期间万古霉素和达托霉素敏感性降低
Diagn Microbiol Infect Dis. 2008 Apr;60(4):437-40. doi: 10.1016/j.diagmicrobio.2007.11.002. Epub 2007 Dec 21.
10
[Treatment of mitral MRSA endocarditis using daptomycin].[使用达托霉素治疗二尖瓣耐甲氧西林金黄色葡萄球菌心内膜炎]
Med Mal Infect. 2008 Dec;38 Spec No 2:13-5. doi: 10.1016/S0399-077X(08)75154-0.

引用本文的文献

1
Empyema necessitans caused by methicillin-resistant Staphylococcus aureus: a case report and literature review.耐甲氧西林金黄色葡萄球菌引起的脓性胸腔积液：一例病例报告并文献复习。
BMC Infect Dis. 2024 Feb 1;24(1):157. doi: 10.1186/s12879-024-09062-0.
2
Intracellular Pharmacokinetics of Antibacterials and Their Clinical Implications.抗菌药物的细胞内药代动力学及其临床意义。
Clin Pharmacokinet. 2018 Feb;57(2):177-189. doi: 10.1007/s40262-017-0572-y.
3
Role of Suppressive Oral Antibiotics in Orthopedic Hardware Infections for Those Not Undergoing Two-Stage Replacement Surgery.
抑制性口服抗生素在未接受两阶段置换手术的骨科植入物感染中的作用。
Open Forum Infect Dis. 2016 Aug 30;3(4):ofw176. doi: 10.1093/ofid/ofw176. eCollection 2016 Oct.
4
Impact of the combination of daptomycin and trimethoprim-sulfamethoxazole on clinical outcomes in methicillin-resistant Staphylococcus aureus infections.达托霉素与甲氧苄啶-磺胺甲恶唑联合使用对耐甲氧西林金黄色葡萄球菌感染临床结局的影响。
Antimicrob Agents Chemother. 2015 Apr;59(4):1969-76. doi: 10.1128/AAC.04141-14. Epub 2015 Jan 20.
5
[Daptomycin for the treatment of gram-positive infections after cardiac surgery].达托霉素用于心脏手术后革兰氏阳性菌感染的治疗
Med Klin Intensivmed Notfmed. 2013 Feb;108(1):59-62. doi: 10.1007/s00063-012-0163-5. Epub 2012 Nov 14.
6
Daptomycin: a novel lipopeptide antibiotic against Gram-positive pathogens.达托霉素：一种针对革兰氏阳性病原体的新型脂肽类抗生素。
Infect Drug Resist. 2010;3:95-101. doi: 10.2147/IDR.S6961. Epub 2010 Aug 30.
7
Daptomycin in treatment of Methicillin-resistant Staphylococcus aureus diskitis.
Neurol Sci. 2011 Aug;32(4):747-8. doi: 10.1007/s10072-011-0491-x. Epub 2011 Feb 16.
8
Rifampin combination therapy for nonmycobacterial infections.利福平联合疗法治疗非分枝杆菌感染。
Clin Microbiol Rev. 2010 Jan;23(1):14-34. doi: 10.1128/CMR.00034-09.