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神经内分泌肿瘤转移至乳腺：一例病例报告及文献综述

Neuroendocrine Tumor Metastases to the Breast: A Case Report and Review of the Literature.

作者信息

Urrego Díaz Jose A, González Marcela, Romero-Rojas Alfredo Ernesto, Strosberg Jonathan, Jiménez-Vásquez Paola

机构信息

Internal Medicine, Universidad Nacional de Colombia, Bogotá, COL.

Radiology, Instituto de Diagnóstico Médico (IDIME), Bogotá, COL.

出版信息

Cureus. 2023 Jun 20;15(6):e40703. doi: 10.7759/cureus.40703. eCollection 2023 Jun.

DOI:10.7759/cureus.40703
PMID:37485220
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10359153/
Abstract

Breast metastases from neuroendocrine neoplasms (NENs) are considered infrequent. We report a case of a patient with ileocecal neuroendocrine tumor (NET) metastases to both breasts, for whom the initial clinical presentation was chronic diarrhea. Breast metastasis was initially suspected by a 68-Gallium DOTANOC positron emission tomography (PET)/CT and was confirmed by histopathology. We also performed a literature review in which we identified 116 cases of NENs metastatic to the breast reported so far. Most cases occurred in older women, were caused by NETs, and had the gastrointestinal tract as the primary site.

摘要

神经内分泌肿瘤（NENs）的乳腺转移被认为较为罕见。我们报告一例患有回盲部神经内分泌肿瘤（NET）并发生双侧乳腺转移的患者，其最初的临床表现为慢性腹泻。乳腺转移最初通过68镓DOTANOC正电子发射断层扫描（PET）/CT怀疑，并经组织病理学证实。我们还进行了文献综述，在此过程中我们确定了迄今为止报告的116例NENs乳腺转移病例。大多数病例发生在老年女性，由NETs引起，且以胃肠道为原发部位。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8f1/10359153/726ca0122249/cureus-0015-00000040703-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8f1/10359153/5df1cae5894c/cureus-0015-00000040703-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8f1/10359153/8841ec59e73e/cureus-0015-00000040703-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8f1/10359153/726ca0122249/cureus-0015-00000040703-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8f1/10359153/5df1cae5894c/cureus-0015-00000040703-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8f1/10359153/8841ec59e73e/cureus-0015-00000040703-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8f1/10359153/726ca0122249/cureus-0015-00000040703-i03.jpg

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