Groneberg David A, Nowak Dennis, Wussow Anke, Fischer Axel
Division of Allergy Research, Otto-Heubner-Centre, Charité School of Medicine, Free University and Humboldt-University, 13353 Berlin, Germany.
J Occup Med Toxicol. 2006 Feb 2;1:3. doi: 10.1186/1745-6673-1-3.
Within the large variety of subtypes of chronic cough, either defined by their clinical or pathogenetic causes, occupational chronic cough may be regarded as one of the most preventable forms of the disease. Next to obstructive airway diseases such as asthma or chronic obstructive pulmonary disease, which are sometimes concomitant with chronic cough, this chronic airway disease gains importance in the field of occupational medicine since classic fiber-related occupational airway diseases will decrease in the future. Apart from acute accidents and incidental exposures which may lead to an acute form of cough, there are numerous sources for the development of chronic cough within the workplace. Over the last years, a large number of studies has focused on occupational causes of respiratory diseases and it has emerged that chronic cough is one of the most prevalent work-related airway diseases. Best-known examples of occupations related to the development of cough are coal miners, hard-rock miners, tunnel workers, or concrete manufacturing workers. As chronic cough is often based on a variety of non-occupational factors such as tobacco smoke, a distinct separation into either occupational or personally -evoked can be difficult. However, revealing the occupational contribution to chronic cough and to the symptom cough in general, which is the commonest cause for the consultation of a physician, can significantly lead to a reduction of the socioeconomic burden of the disease.
在由临床或致病原因定义的多种慢性咳嗽亚型中,职业性慢性咳嗽可被视为该疾病最可预防的形式之一。除了有时与慢性咳嗽并发的阻塞性气道疾病,如哮喘或慢性阻塞性肺疾病外,这种慢性气道疾病在职业医学领域变得越来越重要,因为经典的与纤维相关的职业性气道疾病在未来将会减少。除了可能导致急性咳嗽的急性事故和偶然接触外,工作场所中还有许多导致慢性咳嗽的来源。在过去几年中,大量研究聚焦于呼吸系统疾病的职业病因,并且已发现慢性咳嗽是最常见的与工作相关的气道疾病之一。与咳嗽发生相关的职业中最著名的例子是煤矿工人、硬岩矿工、隧道工人或混凝土制造工人。由于慢性咳嗽通常基于多种非职业因素,如烟草烟雾,因此很难明确区分是职业性还是个人诱发的。然而,揭示职业因素对慢性咳嗽以及一般症状性咳嗽(这是患者就医最常见的原因)的影响,可显著减轻该疾病的社会经济负担。