Ablin R J, Whyard T C
Department of Urology, State University of New York, Stony Brook 11794-8093.
Experientia. 1991 Mar 15;47(3):277-9. doi: 10.1007/BF01958159.
Normal human spermatozoa were demonstrated by dot immunoblot analysis and immunohistochemistry to possess transglutaminase (TGase). The immunological identification of spermatozoal TGase is consistent with reports by others of its biochemical identification and suggested role in sperm motility, and provides, in view of the immunoregulatory properties of seminal plasma TGase, presumptive identification of a means whereby spermatozoa, under normal physiological conditions, may possibly be protected from immunological 'attack' within the female reproductive tract.
通过斑点免疫印迹分析和免疫组织化学证明,正常人精子含有转谷氨酰胺酶(TGase)。精子TGase的免疫学鉴定与其他人关于其生化鉴定及其在精子运动中作用的报道一致,并且鉴于精浆TGase的免疫调节特性,推测鉴定出一种在正常生理条件下精子可能免受女性生殖道内免疫“攻击”的方式。