Bontrop Ronald E
Department of Comparative Genetics and Refinement, Biomedical Primate Research Centre, GH Rijswijk, The Netherlands.
Hum Immunol. 2006 Jun;67(6):388-97. doi: 10.1016/j.humimm.2006.03.007. Epub 2006 Apr 3.
Gene products of the major histocompatibility complex (MHC) play a crucial role in the activation of adaptive (antigen-dependent) immune responses. In this paper similarities and dissimilarities among the MHCs of different primate species and their functional implications are reviewed. The human HLA system represents the most thoroughly investigated MHC of any contemporary living primate species, and so it will serve as a reference.
主要组织相容性复合体（MHC）的基因产物在适应性（抗原依赖性）免疫反应的激活中起着关键作用。本文综述了不同灵长类物种MHC之间的异同及其功能意义。人类HLA系统是当代任何现存灵长类物种中研究最深入的MHC，因此将作为参考。
