人类白细胞抗原与迟发性运动障碍

Human leucocyte antigens and tardive dyskinesia.

作者信息

Brown K W, White T

机构信息

Royal Edinburgh Hospital.

出版信息

Br J Psychiatry. 1991 Feb;158:270-2. doi: 10.1192/bjp.158.2.270.

DOI:10.1192/bjp.158.2.270

PMID:1672828

Abstract

HLA status was assessed in matched groups of schizophrenics, 20 with and 20 without tardive dyskinesia. The antigen frequencies were also compared with that in a control sample. The anticipated excess of HLA-B44 was not confirmed. Pooled data displayed a shortfall of HLA-Cw7 and an excess of HLA-B44 in schizophrenics relative to population controls.

摘要

对精神分裂症患者的配对组进行了HLA状态评估，其中20例有迟发性运动障碍，20例没有迟发性运动障碍。还将抗原频率与对照样本进行了比较。预期的HLA - B44过量未得到证实。汇总数据显示，相对于人群对照，精神分裂症患者中HLA - Cw7不足，HLA - B44过量。