van Nieuw Ameronpn A, Veerman E C I, Brand H S, Vissink A
Afdeling Tandheelkundige Basiswetenschappen, sectie Orale Biochemie van het Academisch Centrum Tandheelkunde Amsterdam.
Ned Tijdschr Tandheelkd. 2006 May;113(5):176-81.
Several salivary proteins are involved in the antimicrobial defence within the oral cavity, and are able to eliminate or inhibit a great number of microorganisms that enter the body via the oral cavity. Thus changes in the composition of saliva may not only affect people's oral health, but also have consequences for their general health. Based on salivary proteins, antimicrobial peptides have been synthesized. Potentially, these could be used as a new class of antibiotics. The antimicrobial peptides are hardly cytotoxic to human cells and do not evoke any or only very little resistence in microorganisms.
几种唾液蛋白参与口腔内的抗菌防御，能够清除或抑制大量经口腔进入人体的微生物。因此，唾液成分的变化不仅可能影响人们的口腔健康，还可能对其整体健康产生影响。基于唾液蛋白，人们合成了抗菌肽。这些抗菌肽有可能用作新型抗生素。抗菌肽对人体细胞几乎没有细胞毒性，并且在微生物中不会引起任何抗性或只会引起非常小的抗性。
