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唾液在维持口腔健康及辅助诊断方面的作用。

The rôle of saliva in maintaining oral health and as an aid to diagnosis.

作者信息

Llena-Puy Carmen

机构信息

Department 9, Valencian Health Service, CEU Cardenal Herrera University.

出版信息

Med Oral Patol Oral Cir Bucal. 2006 Aug;11(5):E449-55.

Abstract

Saliva is a complex secretion. 93% by volume is secreted by the major salivary glands and the remaining 7% by the minor glands. 99% of saliva is water and the other 1% is composed of organic and inorganic molecules. While the quantity of saliva is important, so is its quality. The components of saliva, its functions in maintaining oral health and the main factors that cause alterations in salivary secretion will be reviewed, the importance of saliva in caries development and bacterial plaque formation will be discussed and its role as an aid to diagnosing certain pathologies will be examined. Variations in salivary flow can be affected, reversibly or irreversibly, by numerous physiological and pathological factors. Saliva plays an essential role in maintaining the integrity of the oral structures, in personal relationships, in the digestion and in controlling oral infection. The part that saliva plays in protecting teeth from caries can be summarised under four aspects: diluting and eliminating sugars and other substances, buffer capacity, balancing demineralisation/remineralisation and antimicrobial action. Saliva is a promising option for diagnosing certain disorders and monitoring the evolution of certain pathologies or the dosage of medicines or drugs. Its advantages as a diagnostic tool include its being easy to obtain and the positive correlation between many parameters in serum and saliva.

摘要

唾液是一种复杂的分泌物。按体积计算,93%由大唾液腺分泌,其余7%由小唾液腺分泌。99%的唾液是水,另外1%由有机和无机分子组成。唾液的量固然重要,其质量也同样重要。本文将综述唾液的成分、其在维持口腔健康中的功能以及导致唾液分泌改变的主要因素,讨论唾液在龋齿发展和牙菌斑形成中的重要性,并研究其作为辅助诊断某些病症的作用。唾液流量的变化可受到多种生理和病理因素的可逆或不可逆影响。唾液在维持口腔结构的完整性、人际关系、消化以及控制口腔感染方面发挥着重要作用。唾液在保护牙齿免受龋齿侵害方面的作用可概括为四个方面:稀释和清除糖分及其他物质、缓冲能力、平衡脱矿质/再矿化以及抗菌作用。唾液是诊断某些疾病以及监测某些病症的进展或药物剂量的一个有前景的选择。其作为诊断工具的优点包括易于获取以及血清和唾液中许多参数之间存在正相关。

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