van der Gaag Mark, Hoffman Tonko, Remijsen Mila, Hijman Ron, de Haan Lieuwe, van Meijel Berno, van Harten Peter N, Valmaggia Lucia, de Hert Marc, Cuijpers Anke, Wiersma Durk
Parnassia Psychiatric Institute, Oude Haagweg 353, The Hague, The Netherlands.
Schizophr Res. 2006 Jul;85(1-3):280-7. doi: 10.1016/j.schres.2006.03.021. Epub 2006 May 26.
The lack of fit of 25 previously published five-factor models for the PANSS items, can be due to the statistics used. The purpose of this study was to use a 'new' statistical method to develop and confirm an improved five-factor model. The improved model is both complex and stable. Complex means that symptoms can have multiple factor loadings, because they have multiple causes, not because they are ill defined. Stable means that the complex structure is found repeatedly in validations.
A ten-fold cross-validation (10 CV) was applied on a large data set (N = 5769) to achieve an improved factor model for the PANSS items. The advantages of 10 CV are minimal effect of sample characteristics and the ability to investigate the stability of items loading on multiple factors.
The results show that twenty-five items contributed to the same factor all ten validations with one item showing a consistent loading on two factors. Three items were contributing to the same factor nine out of ten validations, and two items were contributing to the same factor six to eight times. The resulting five-factor model covers all thirty items of the PANSS, subdivided in the factors: positive symptoms, negative symptoms, disorganization, excitement, and emotional distress. The five-factor model has a satisfactory goodness-of-fit (Comparative Fit Index = .905; Root Mean Square Error of Approximation = .052).
The five-factor model developed in this study is an improvement above previously published models as it represents a complex factor model and is more stable.
之前发表的25个针对阳性和阴性症状评定量表(PANSS)项目的五因素模型拟合不佳,可能是由于所使用的统计方法。本研究的目的是使用一种“新”的统计方法来开发并验证一个改进的五因素模型。该改进模型既复杂又稳定。复杂意味着症状可以有多个因子负荷,这是因为它们有多种原因,而非定义不明确。稳定意味着在验证中能反复发现这种复杂结构。
对一个大数据集(N = 5769)应用十折交叉验证(10 CV),以获得针对PANSS项目的改进因子模型。10 CV的优点是样本特征影响最小,且有能力研究项目在多个因子上负荷的稳定性。
结果显示,25个项目在所有十次验证中都归为同一因子,有一个项目在两个因子上的负荷一致。三个项目在十次验证中有九次归为同一因子,两个项目在六至八次验证中归为同一因子。由此得到的五因素模型涵盖了PANSS的所有30个项目,细分为以下因子:阳性症状、阴性症状、紊乱、兴奋和情绪困扰。该五因素模型具有令人满意的拟合优度(比较拟合指数 = 0.905;近似均方根误差 = 0.052)。
本研究中开发的五因素模型比之前发表的模型有所改进,因为它代表了一个复杂的因子模型且更稳定。