Bortolotti de Mello Jacobucci Maria Silvia, Guazzelli Cristina Aparecida Falbo, Barbieri Márcia, Araújo Fabio Fernando, Moron Antonio Fernandes
Family Planning Clinic, Department of Obstetrics and Gynecology, São Paulo Federal University, São Paulo, Brazil.
Contraception. 2006 Jun;73(6):594-7. doi: 10.1016/j.contraception.2006.01.009. Epub 2006 Mar 29.
This prospective observational study evaluated the bleeding patterns of adolescents receiving a monthly injectable contraceptive containing norethisterone enanthate 50 mg plus estradiol valerate 5 mg.
The study enrolled 73 volunteers aged between 14 and 19 years; of these patients, 38 (52%) recorded their menstrual cycles during 1 year.
After 1 year of using the contraceptive, most of the 38 women (71.1%) had adequate menstrual patterns (two to four bleeding episodes; none lasting 10 days or longer; with a range of bleeding-free intervals not exceeding 17 days), 23.7% reported prolonged bleeding episodes, 2.6% had irregular bleeding and 2.6% had amenorrhea. Only 1 of the 38 teenagers is known to have discontinued the method due to bleeding. Among these 38 adolescents, dissatisfaction with bleeding patterns was not a frequent reason given for discontinuation of the monthly injectable contraceptive.
这项前瞻性观察性研究评估了接受含50毫克庚酸炔诺酮加5毫克戊酸雌二醇的每月注射用避孕药的青少年的出血模式。
该研究招募了73名年龄在14至19岁之间的志愿者;在这些患者中,38名(52%)在1年内记录了她们的月经周期。
使用避孕药1年后,38名女性中的大多数(71.1%)月经模式正常(有两到四次出血事件;没有一次持续10天或更长时间;无出血间隔时间范围不超过17天),23.7%报告有出血时间延长的情况,2.6%有不规则出血,2.6%有闭经。已知38名青少年中只有1人因出血而停用该方法。在这38名青少年中,对出血模式不满意并不是停用每月注射用避孕药的常见原因。