Fletcher Margaret, Leeming John, Cartwright Keith, Finn Adam
Faculty of Health and Social Care, University of the West of England, Bristol, UK.
Pediatr Infect Dis J. 2006 Jun;25(6):559-60. doi: 10.1097/01.inf.0000219535.14201.1b.
During 2003-2004, locally presenting pleural empyema cases in children increased 3-fold. Antigen analysis of empyema fluid identified Streptococcus pneumoniae in 27 of 29 cases for whom samples were available and capsular polysaccharide type 1 in 18 of these. Use of a conjugate vaccine without serotype 1 antigen would have had limited impact on this morbidity in our region.
在2003年至2004年期间，当地儿童胸膜脓胸病例增加了两倍。对脓胸液进行的抗原分析显示，在可获取样本的29例病例中，有27例检测出肺炎链球菌，其中18例为1型荚膜多糖。在我们地区，使用不含1型抗原的结合疫苗对这种发病率的影响有限。
