Snir M, Bachar M, Katz J, Friling R, Weinberger D, Axer-Siegel R
Pediatric Ophthalmology and Strabismus Unit, Schneider Children's Medical Center of Israel, Petach-Tikva, Israel.
Eye (Lond). 2007 Sep;21(9):1155-61. doi: 10.1038/sj.eye.6702426. Epub 2006 May 26.
To evaluate the safety and efficacy of propofol sedation combined with sub-Tenon's anaesthesia for strabismus surgery in adults.
Thirty-two consecutive patients aged 31-85 years underwent strabismus surgery under general (n=16) or local (n=16) anaesthesia. In the local anaesthesia (study) group, sedation was induced with a loading dose of midazolam, fentanyl, and propofol, followed by continuous infusion of propofol, 3-6 mg/k/h to deep sedation. A nasal tube was inserted to prevent airway obstruction. Sub-Tenon's anaesthesia included infusion of a 3-4 ml mixture (50 : 50) of lidocaine 2%/mercaine 0.5%. General anaesthesia consisted of premedication with midazolam, followed by fentanyl, esmeron-bromate, propofol, and tracheal intubation. Duration of surgery and anaesthesia, intraoperative oculocardiac reflex and arrhythmias, time to discharge, postoperative pain, nausea and vomiting, and patient and surgeon satisfaction were evaluated.
The local anaesthesia group had a significantly shorter operative and anaesthesia time, fewer episodes of oculocardiac reflex or arrythmia/bradycardia requiring treatment, fewer early or late episodes of nausea and vomiting, and less pain. The patients and surgeon in this group reported higher satisfaction.
Propofol sedation with local sub-Tenon's injection of lidocaine/mercaine is recommended for the induction and maintenance of anaesthesia during unilateral or bilateral strabismus surgery in adults. The method is quick and effective, without systemic or ocular side effects.
评估丙泊酚镇静联合球后麻醉用于成人斜视手术的安全性和有效性。
32例年龄在31至85岁之间的连续患者接受斜视手术,其中16例接受全身麻醉,16例接受局部麻醉。在局部麻醉(研究)组中,先给予负荷剂量的咪达唑仑、芬太尼和丙泊酚诱导镇静,随后持续输注丙泊酚,剂量为3 - 6毫克/千克/小时,直至深度镇静。插入鼻导管以防止气道阻塞。球后麻醉包括注入3 - 4毫升2%利多卡因/0.5%丙美卡因的混合液(50:50)。全身麻醉包括术前给予咪达唑仑,随后给予芬太尼、依托咪酯、丙泊酚并进行气管插管。评估手术和麻醉持续时间、术中眼心反射和心律失常、出院时间、术后疼痛、恶心和呕吐以及患者和外科医生的满意度。
局部麻醉组的手术和麻醉时间明显更短,需要治疗的眼心反射或心律失常/心动过缓发作次数更少,早期或晚期恶心和呕吐发作次数更少,疼痛也更轻。该组患者和外科医生报告的满意度更高。
推荐在成人单侧或双侧斜视手术中,采用丙泊酚镇静联合局部球后注射利多卡因/丙美卡因来诱导和维持麻醉。该方法快速有效,无全身或眼部副作用。