Kaza R K, Gulati M, Wig J D, Chawla Y K
Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Australas Radiol. 2006 Jun;50(3):212-7. doi: 10.1111/j.1440-1673.2006.01564.x.
The objective of this study is to evaluate the efficacy of dynamic MRI with magnetic resonance cholangiopancreatography (MRCP) in the preoperative assessment of gall bladder carcinoma. Magnetic resonance imaging and MRCP were carried out in 15 patients with gall bladder carcinoma before surgery and the imaging findings correlated with surgical and pathological findings. Gall bladder carcinoma manifested as focal or diffuse wall thickening in 73% (11/15) and as a mass replacing the gall bladder in 27% (4/15). All tumours showed enhancement in the early phase, which persisted into the delayed phase. The sensitivity and specificity of MRI with MRCP in detecting hepatic invasion, lymph node metastasis and bile duct invasion was 87.5 and 86%, 60 and 90%, and 80 and 100%, respectively. Magnetic resonance imaging correctly diagnosed duodenal invasion in only 50% and in none of the two patients with peritoneal metastasis. In conclusion, dynamic MRI with MRCP is an accurate and a reliable method of showing gall bladder carcinoma and in assessing its local and regional extent as part of preoperative assessment.
本研究的目的是评估动态磁共振成像联合磁共振胰胆管造影（MRCP）在胆囊癌术前评估中的疗效。对15例胆囊癌患者在手术前进行了磁共振成像和MRCP检查，并将影像学表现与手术及病理结果进行了对比。73%（11/15）的胆囊癌表现为局灶性或弥漫性壁增厚，27%（4/15）表现为肿块取代胆囊。所有肿瘤在早期均有强化，并持续至延迟期。MRI联合MRCP检测肝侵犯、淋巴结转移和胆管侵犯的敏感性和特异性分别为87.5%和86%、60%和90%、80%和100%。磁共振成像仅正确诊断出50%的十二指肠侵犯，在两名有腹膜转移的患者中均未诊断出。总之，动态MRI联合MRCP是显示胆囊癌并评估其局部和区域范围的一种准确且可靠的方法，可作为术前评估的一部分。
